CD21 Antibody (1F8)

CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signaling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NBP1-22527	Applications	Species
M Ukita, J Hamanishi, H Yoshitomi, K Yamanoi, S Takamatsu, A Ueda, H Suzuki, Y Hosoe, Y Furutake, M Taki, K Abiko, K Yamaguchi, H Nakai, T Baba, N Matsumura, A Yoshizawa, H Ueno, M Mandai CXCL13-producing CD4+ T cells accumulate in early phase of tertiary lymphoid structures in ovarian cancer JCI Insight, 2022-06-22;0(0):. 2022-06-22 [PMID: 35552285]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IHC-P	Human	01/27/2021	View Summary Application Immunohistochemistry-Paraffin Sample Tested human tonsil Species Human Lot P827
Enlarge	4 reviewed by: Verified Customer	IHC-P	Cynomolgus Monkey	01/27/2021	View Summary Application Immunohistochemistry-Paraffin Sample Tested cynomolgus monkey spleen Species Cynomolgus Monkey Lot P827 Comments Comments 1:10 & 1:25 dilutions were tested on human tonsil and cynomolgus monkey spleen and tonsil tissue. An anti-mouse polymer was used for detection. The human tonsil stained nicely, but there was no staining in the monkey tissues.

Array NBP1-22527

• CD21 Antibodies
• CD21 Antibody Pair
• CD21 ELISA Kits
• CD21 Proteins
• CD21 ELISA
• CD21 Proteins and Enzyme