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CCAR1 Antibody

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Western Blot: CCAR1 Antibody [NBP1-46158] - NBP1-46158 (1ug/ml) staining of Rat Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Mu, Rt, Hu, Po, Bv, CaSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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CCAR1 Antibody Summary

Immunogen
Peptide with sequence RYCKERPSKDKE corresponding to internal region (near C-Terminus) according to NP_060707.2.
Epitope
internal region (near C-Terminus)
Predicted Species
Human (100%), Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCAR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 120 kDa band observed in mouse and rat skeletal muscle lysates (calculated MW of 132 kDa band according to mouse NP_080477.1 and rat NP_001102005.1). An additional band of unknown identity was also consistently observed at 33 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Publications
Read Publication using NBP1-46158.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCAR1 Antibody

  • CARP-1
  • CARP1MGC44628
  • Cell cycle and apoptosis regulatory protein 1
  • cell division cycle and apoptosis regulator 1
  • cell division cycle and apoptosis regulator protein 1
  • Death inducer with SAP domain
  • DIS
  • FLJ10590
  • RP11-437A18.1

Background

CCAR1 was identified as a perinuclear phosphoprotein that regulates apoptosis signals in response to chemotherapeutic agents. Induction of apoptosis by CCAR1 involves the epidermal growth factor receptor (EGFR), mitogen-activated protein kinase pathway and caspase-9 activation. CARP-1 has also been demonstrated as a suppressor of human breast cancer growth. CCAR1 is also known as cell division cycle and apoptosis regulator protein 1, cell cycle and apoptosis regulatory protein 1, CARP-1, death inducer with SAP domain, DIS, MGC44628, and RP11-437A18.1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ELISA

Publications for CCAR1 Antibody (NBP1-46158)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for CCAR1 Antibody (NBP1-46158) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CCAR1 Products

Array NBP1-46158

Research Areas for CCAR1 Antibody (NBP1-46158)

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Blogs on CCAR1

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Bioinformatics

Gene Symbol CCAR1
Entrez
Uniprot