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Cannabinoid R2/CB2/CNR2 Antibody (352110R) [PE/Atto594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
352110R
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Atto594

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Cannabinoid R2/CB2/CNR2 Antibody (352110R) [PE/Atto594] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human embryonic kidney cell line HEK293-derived transfected with human Cannabinoid R2/CB2/CNR2
Met1-Cys360
Accession # NP_001832
Specificity
Detects human Cannabinoid R2/CB2/CNR2 in HEK293 human cell line transfected with human Cannabinoid R2/CB2/CNR2 and not Cannabinoid R1/CB1/CNR1 transfectants in flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for Cannabinoid R2/CB2/CNR2 Antibody (352110R) [PE/Atto594]

  • Cannabinoid R2
  • cannabinoid receptor 2 (macrophage)
  • CannabinoidR2
  • CB-2
  • CB2cannabinoid receptor 2
  • CB2R
  • CNR2
  • CX5
  • CX5testis-dominant CNR2 isoform CB2
  • hCB2

Background

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cannabinoid R2/CB2/CNR2 Antibody (FAB36551RPEATT594) (0)

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