beta I Tubulin Antibody (923425) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

beta -tubulin is a 50 kDa cytoskeletal protein which is the a major component of neuronal processes: axons, dendrites, and dendritic spines. beta -tubulin is represented by different isoforms including beta -I, beta -II, beta -III, and beta -IV. Elimination of beta -I isoform will decrease the viability of neuroblastoma cells. Formation of actin tubules may be directly inhibited by beta -I isoform which results in decreasing cellular adhesion. beta -I Tubulin levels in different brain regions of schizophrenia patients  undergo noticeable changes suggesting that this isoform may have a specific role in the pathophysiology of this illness by affecting actin tubule formation which is required for cell division and differentiation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Transgenic Mouse.

We have publications tested in 4 applications: Cell Culture, ICC, Western Blot, Western Blot Control.

Showing Publications 1 - 5 of 5.

Publications using MAB8527	Applications	Species
A Herbst, S Wohlgemuth, J Yang, AR Castle, DM Moreno, A Otero, JM Aiken, D Westaway, D McKenzie Susceptibility of Beavers to Chronic Wasting Disease Biology, 2022-04-26;11(5):. 2022-04-26 [PMID: 35625395] (Western Blot, Transgenic Mouse)	Western Blot	Transgenic Mouse
B Jiang, A White, W Ou, S Van Belleg, S Stewart, JG Shamul, SO Rahaman, JP Fisher, X He Noncovalent reversible binding-enabled facile fabrication of leak-free PDMS microfluidic devices without plasma treatment for convenient cell loading and retrieval Bioactive materials, 2022-03-16;16(0):346-358. 2022-03-16 [PMID: 35386332] (ICC, Human)	ICC	Human
D Romaniello, I Marrocco, N Belugali N, I Ferrer, D Drago-Garc, I Vaknin, R Oren, M Lindzen, S Ghosh, M Kreitman, JC Kittel, N Gaborit, G Bergado Ba, B Sanchez, R Eilam, E Pikarsky, L Paz-Ares, Y Yarden Targeting HER3, a Catalytically Defective Receptor Tyrosine Kinase, Prevents Resistance of Lung Cancer to a Third-Generation EGFR Kinase Inhibitor Cancers (Basel), 2020-08-24;12(9):. 2020-08-24 [PMID: 32847130] (Cell Culture, Western Blot Control, Human)	Cell Culture, Western Blot Control	Human
Sara M. Ibrahim, Sherin Bakhashab, Asad M. Ilyas, Peter N. Pushparaj, Sajjad Karim, Jalaluddin A. Khan et al. WYE-354 restores Adriamycin sensitivity in multidrug-resistant acute myeloid leukemia cell lines Oncology Reports 4/2/2019 [PMID: 30942458]
MA Davis, MR Fairgrieve, A Den Hartig, O Yakovenko, B Duvvuri, C Lood, WE Thomas, SL Fink, M Gale Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation Proc. Natl. Acad. Sci. U.S.A., 2019-02-22;0(0):. 2019-02-22 [PMID: 30796192] (Western Blot, Human)	Western Blot	Human

Array MAB8527

• beta I Tubulin Antibodies
• beta I Tubulin Lysate
• beta I Tubulin Protein