BAG3 Antibody

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using NBP2-15543	Applications	Species
Nymoen DA, Hetland Falkenthal TE, Holth A et al. Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma. Gynecol. Oncol. 2015-07-29 [PMID: 26232338] (IHC-P, Human)	IHC-P	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Ben Davidson	IHC-P	Human	01/30/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested Human ovarian carcinoma Species Human Lot AR100-112619-04 Comments Comments 1:100 dilution, pH=6 retrieval buffer, Dako FLEX+ protocol

Array NBP2-15543

• BAG3 Antibodies
• BAG3 ELISA Kit
• BAG3 Proteins