Home » BAFF/BLyS/TNFSF13B » BAFF/BLyS/TNFSF13B Antibodies » BAFF/BLyS/TNFSF13B Antibody (148725) [Unconjugated]
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BAFF/BLyS/TNFSF13B Antibody (148725) [Unconjugated]

 (6 Publications)
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Recombinant Human BAFF/BLyS/TNFSF13B (Catalog # 2149-BF) stimulates proliferation in mouse B cells in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human BAFF/BLyS/TNFSF13B (5 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human BAFF/BLyS/TNFSF13B Monoclonal Antibody (Catalog # MAB124). At 20 µg/mL, this anti-BAFF/BLyS/TNFSF13B antibody will neutralize >60% of Recombinant Human BAFF/BLyS/TNFSF13B-induced proliferation of mouse B cells.
Recombinant Human BAFF/BLyS/TNFSF13B (Catalog # 2149-BF) stimulates proliferation in mouse B cells in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human BAFF/BLyS/TNFSF13B (5 ng/mL) is ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications B/N
Clone
148725
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB124-SP
Carrier Free
MAB124-500
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BAFF/BLyS/TNFSF13B Antibody (148725) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human BAFF
Ala134-Leu285
Accession # Q9Y275
Specificity
Detects human BAFF in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TNFSF13B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Neutralization 20 ug/mL
Publications
Read Publications using
MAB124 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BAFF/BLyS/TNFSF13B Antibody (148725) [Unconjugated]

  • ApoL related ligand TALL-1
  • B lymphocyte stimulator
  • BAFF
  • BAFFB-cell activating factor
  • B-cell-activating factor
  • BLyS
  • BLYSB-lymphocyte stimulator
  • CD257 antigen
  • CD257
  • Dendritic cell-derived TNF-like molecule
  • DTL
  • TALL1
  • TALL-1delta BAFF
  • TALL1Delta4 BAFF
  • THANK
  • TNF- and APOL-related leukocyte expressed ligand 1
  • TNF and ApoL-related leukocyte expressed ligand 1
  • TNF homolog that activates apoptosis
  • TNFSF13B
  • TNFSF20
  • tumor necrosis factor (ligand) superfamily, member 13b
  • tumor necrosis factor (ligand) superfamily, member 20
  • tumor necrosis factor ligand superfamily member 13B
  • tumor necrosis factor superfamily, member 13b
  • tumor necrosis factor-like protein ZTNF4
  • ZTNF4

Background

BAFF, also known as B-lymphocyte stimulator (BLyS), TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1), and TNF homolog that activates apoptosis, NFKB and JNK (THANK), is a TNF ligand superfamily member and has been designated TNFSF13B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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BAFF/BLyS/TNFSF13B
Antibody (148725) [Un ...
MAB124
BAFF/BLyS/TNFSF13B Antibody (148725) [Unconjugated]
Species: Hu
Applications: B/N

Publications for BAFF/BLyS/TNFSF13B Antibody (MAB124)(6)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow Cytometry, ICC, Neutralization.


Filter By Application
Flow Cytometry
(1)
ICC
(1)
Neutralization
(4)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 6 of 6.
Publications using MAB124 Applications Species
H Touil, A Kobert, N Lebeurrier, A Rieger, P Saikali, C Lambert, L Fawaz, CS Moore, A Prat, J Gommerman, JP Antel, Y Itoyama, I Nakashima, A Bar-Or Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis J Neuroinflammation, 2018-04-19;15(1):114. 2018-04-19 [PMID: 29673365] (Neutralization, Human) Neutralization Human
Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis Sci Rep, 2016-11-18;6(0):36862. 2016-11-18 [PMID: 27857173] (Neutralization, Human) Neutralization Human
Giacomini E, Severa M, Rizzo F, Mechelli R, Annibali V, Ristori G, Riccieri V, Salvetti M, Coccia E IFN-beta therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients. Eur J Immunol, 2013-05-28;43(7):1963-72. 2013-05-28 [PMID: 23636665] (Neutralization, Human) Neutralization Human
Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival. PLoS ONE, 2012-07-09;7(7):e40620. 2012-07-09 [PMID: 22792388] (Flow Cytometry, Neutralization, Human) Flow Cytometry, Neutralization Human
Hallock PT, Xu CF, Park TJ Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev., 2010-11-01;24(21):2451-61. 11/1/2010 [PMID: 21041412]
Fu L, Lin-Lee YC, Pham LV, Tamayo A, Yoshimura L, Ford RJ Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas. Blood, 2006-02-23;107(11):4540-8. 2006-02-23 [PMID: 16497967] (ICC, Human) ICC Human

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Bioinformatics

Gene Symbol TNFSF13B
Uniprot