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BACE-2 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77309AF350
Alexa Fluor 405
NBP1-77309AF405
Alexa Fluor 488
NBP1-77309AF488
Alexa Fluor 532
NBP1-77309AF532
Alexa Fluor 594
NBP1-77309AF594
Alexa Fluor 647
NBP1-77309AF647
Alexa Fluor 700
NBP1-77309AF700
Alexa Fluor 750
NBP1-77309AF750
Biotin
NBP1-77309B
CoraFluor 1
NBP1-77309CL1
DyLight 350
NBP1-77309UV
DyLight 405
NBP1-77309V
DyLight 488
NBP1-77309G
DyLight 594
NBP1-77309DL594
DyLight 650
NBP1-77309C
DyLight 680
NBP1-77309FR
DyLight 755
NBP1-77309IR
FITC
NBP1-77309F
HRP
NBP1-77309H
Janelia Fluor 525
NBP1-77309JF525
Janelia Fluor 549
NBP1-77309JF549
Janelia Fluor 585
NBP1-77309JF585
Janelia Fluor 635
NBP1-77309JF635
Janelia Fluor 646
NBP1-77309JF646
Janelia Fluor 669
NBP1-77309JF669
PerCP
NBP1-77309PCP
Unconjugated
NBP1-77309
mFluor Violet 450 SE
NBP1-77309MFV450
mFluor Violet 500 SE
NBP1-77309MFV500
mFluor Violet 610 SE
NBP1-77309MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77309
BSA Free
NBP1-77309
BSA Free
NBP1-77309-0.025mg
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BACE-2 Antibody [DyLight 550] Summary

Immunogen
Antibody was raised against a 16 amino acid peptide near the amino terminus of human BACE2. The immunogen is located within amino acids 30 - 80 of BACE2. Amino Acid Squence: APTPGPGTPAERHADG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BACE2
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BACE-2 Antibody [DyLight 550]

  • AEPLC
  • Asp 1
  • ASP1
  • ASP21
  • Aspartic-like protease 56 kDa
  • Aspartyl protease 1
  • BACE2
  • BACE-2
  • beta secretase 2
  • beta-secretase 2
  • beta-site amyloid beta A4 precursor protein-cleaving enzyme 2
  • Beta-site amyloid precursor protein cleaving enzyme 2
  • Beta-site APP cleaving enzyme 2
  • beta-site APP-cleaving enzyme 2
  • beta-site APP-cleaving enzyme 2, EC 3.4.2310ALP5656 kDa aspartic-like protease
  • CEAP1
  • Down region aspartic protease
  • Down syndrome region aspartic protease
  • DRAPBAE2
  • EC 3.4.23
  • EC 3.4.23.45
  • memapsin-1
  • Membrane-associated aspartic protease 1
  • theta-secretase
  • transmembrane aspartic proteinase Asp1

Background

BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BACE2