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Aurora C Antibody

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Western Blot: Aurora C Antibody [NBP1-52004] - Analysis of Aurora C in Human Testis lysate (35ug protein in RIPA buffer) using NBP1-52004 at 1.5 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Aurora C Antibody Summary

Immunogen
Peptide with sequence PRAVVQLGKAQP-C corresponding to N-Terminus according to NP_001015878.1.
Epitope
PRAVVQLGKAQP-C
Specificity
This antibody is expected to recognize isoform 1 (NP_001015878.1) only.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
AURKC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 36 kDa band observed in human testis lysates (calculated MW of 35.6 kDa band according to NP_001015878.1).
Publications
Read Publication using NBP1-52004.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Aurora C Antibody

  • AIE2
  • AIE2AIK3
  • AIK3
  • AIRK3
  • ARK3
  • ARK-3
  • ARK3Serine/threonine-protein kinase aurora-C
  • AurC
  • AURKC
  • Aurora 3
  • Aurora C
  • aurora kinase CAurora/IPL1/Eg2 protein 2
  • Aurora/IPL1-related kinase 3
  • aurora-C
  • Aurora-related kinase 3
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine kinase 13 (aurora/IPL1-like)
  • serine/threonine-protein kinase 13
  • STK13
  • STK13ARK-3

Background

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Aurora C Antibody (NBP1-52004)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AURKC
Entrez
Uniprot