Home » APLP-1 » APLP-1 Antibodies » APLP-1 Antibody [Unconjugated]
Novus Biologicals products are now on bio-techne.com

APLP-1 Antibody [Unconjugated]

 (2 Publications)
 
 See All Related
Submit a Review

Images

 
(
Enlarge)
APLP‑1 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human APLP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3129) at 0.3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in neurons. Staining was performed using out protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
APLP‑1 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human APLP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3129) at ...read more
Simple Western lane view shows lysates of human brain (hippocampus) and mouse brain (hippocampus), loaded at 0.2 mg/mL. A specific band was detected for APLP‑1 at approximately 119 kDa (as indicated) using 25 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western, IHC, IP
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF3129-SP
Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

APLP-1 Antibody [Unconjugated] Summary

Specificity
Detects human APLP‑1 in Western blots. In Western blots, approximately 15% cross-reactivity with recombinant mouse APLP-1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
APLP1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 0.3-15 ug/mL
  • Immunoprecipitation 25 ug/mL
  • Simple Western 25 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF3129 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for APLP-1 Antibody [Unconjugated]

  • amyloid beta (A4) precursor-like protein 1
  • amyloid precursor-like protein 1
  • amyloid-like protein 1
  • APLP1
  • APLP-1
  • APLPAPLP-1

Background

APLP-1 is a transmembrane metalloprotein that is expressed in central neurons. Similar to APP and APLP-2, APLP-1 is susceptible to cleavage by various secretases, generating multiple fragments from the extracellular and intracellular domains. These include peptides similar to the amyloidogenic A beta peptides and a cytoplasmic fragment that associates with Fe65 family proteins and functions as a transcriptional activator. The extracellular domain contains heparin and collagen binding regions and is 89% identical between human and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

beta Amyloid
Antibody (MOAB-2) - B ...
NBP2-13075
Immunohistochemistry-Frozen beta Amyloid Antibody (MOAB-2) - BSA Free
Immunohistochemistry beta Amyloid Antibody (MOAB-2) - BSA Free
Immunocytochemistry/ Immunofluorescence beta Amyloid Antibody (MOAB-2) - BSA Free
(2 Reviews)
(69 Publications)
Species: Ba, Hu, Pm, Mu, Rt
Applications: DB, ELISA, IB, ICC/IF, IHC-FrFl, IHC, IHC-Fr, IHC-P, IP, WB
APLP-2 Antibody
(397702)
MAB49451
Western Blot APLP-2 Antibody (397702)
(2 Publications)
Species: Hu
Applications: WB
FE65 Antibody -
BSA Free
NB110-58360
Western Blot FE65 Antibody - BSA Free
Western Blot FE65 Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: IP, WB
Presenilin-1
Antibody (APS 18)
NB100-74510
Western Blot Presenilin-1 Antibody (APS 18)
Immunocytochemistry/ Immunofluorescence Presenilin-1 Antibody (APS 18)
Immunocytochemistry/ Immunofluorescence Presenilin-1 Antibody (APS 18)
(1 Review)
(5 Publications)
Species: Hu, Mu, Pm, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
BACE-1 Antibody
(137612)
MAB931
Western Blot BACE-1 Antibody (137612)
(15 Publications)
Species: Hu, Mu
Applications: CyTOF-ready, IHC, ICFlow, WB
PrPC Antibody
NB100-56605
Western Blot PrPC Antibody
Species: Av, Bv, Sh
Applications: WB
ATP6V0A4 Antibody
NBP1-89330
Immunohistochemistry-Paraffin ATP6V0A4 Antibody
Immunohistochemistry-Paraffin ATP6V0A4 Antibody
Immunohistochemistry-Paraffin ATP6V0A4 Antibody
Species: Hu
Applications: IHC, IHC-P
gamma Sarcoglycan
Antibody
NBP1-90299
Immunohistochemistry-Paraffin gamma Sarcoglycan Antibody
Immunohistochemistry-Paraffin gamma Sarcoglycan Antibody
Immunocytochemistry/ Immunofluorescence gamma Sarcoglycan Antibody
(1 Review)
Species: Hu
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
Recombinant Human
PLP2 GST (N-Term) Pro ...
H00005355-P01
SDS-PAGE Recombinant Human PLP2 GST (N-Term) Protein
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
APPL Antibody
(OTI4B11)
NBP2-46536
Western Blot APPL Antibody (OTI4B11)
Immunohistochemistry-Paraffin APPL Antibody (OTI4B11)
Immunohistochemistry-Paraffin APPL Antibody (OTI4B11)
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
Presenilin-2
Antibody (APS 26)
NB100-74513
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Species: Hu, Mu, Pm, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
JNK1 Antibody
(228601) [Unconjugate
MAB17761
Western Blot JNK1 Antibody (228601) [Unconjugated]
Western Blot JNK1 Antibody (228601) [Unconjugated]
Immunocytochemistry JNK1 Antibody (228601) [Unconjugated]
(1 Review)
(3 Publications)
Species: Hu, Mu, Rt
Applications: ICC, WB
APBB2 Antibody
NBP1-84700
Western Blot APBB2 Antibody
Western Blot APBB2 Antibody
Immunohistochemistry-Paraffin APBB2 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, KD, WB
CS Citrate
Synthase Antibody (17
NBP2-43648
Western Blot CS Citrate Synthase Antibody (1761)
Western Blot CS Citrate Synthase Antibody (1761)
Western Blot CS Citrate Synthase Antibody (1761)
(1 Review)
(1 Publication)
Species: Hu, Mu, Rt, Ze
Applications: ICC/IF, IHC, IHC-P, WB
Neprilysin/CD10
Antibody [Unconjugate
AF1126
Immunohistochemistry Neprilysin/CD10 Antibody [Unconjugated]
Western Blot Neprilysin/CD10 Antibody [Unconjugated]
Western Blot Neprilysin/CD10 Antibody [Unconjugated]
(22 Publications)
Species: Mu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, IP, WB
ADAM10
[Unconjugated]
936-AD
ADAM10 [Unconjugated]
(24 Publications)
Species: Hu
Applications: EnzAct
Clusterin/APOJ
Antibody
AF2747
Immunohistochemistry Clusterin/APOJ Antibody
Immunohistochemistry Clusterin/APOJ Antibody
Western Blot Clusterin/APOJ Antibody
(13 Publications)
Species: Mu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, IP, WB
APLP-1 Antibody
[Unconjugated]
AF3129
APLP-1 Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, IHC, IP

Publications for APLP-1 Antibody (AF3129)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


Filter By Application
Western Blot
(1)
All Applications
Filter By Species
Human
(1)
All Species

Reviews for APLP-1 Antibody (AF3129) (0)

There are no reviews for APLP-1 Antibody (AF3129). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for APLP-1 Antibody (AF3129) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional APLP-1 Products

Blogs on APLP-1

There are no specific blogs for APLP-1, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our APLP-1 Antibody [Unconjugated] and receive a gift card or discount.


Bioinformatics

Gene Symbol APLP1
Uniprot