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ALS2CR2 Antibody

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Western Blot: ALS2CR2 Antibody [NBP2-24680] - analysis of Als2Cr2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse brain using Als2Cr2 antibody at 4.0 ug/ml and 2 ug/ml, ...read more
Immunohistochemistry-Paraffin: ALS2CR2 Antibody [NBP2-24680] - Formalin-fixed, paraffin-embedded human kidney stained with Als2Cr2 antibody at 20 ug/ml. Tubule staining can be seen. Staining of formalin-fixed tissues is ...read more

Product Details

Summary
Reactivity Hu, Bv, Ca, Eq, Pm, Mu, Rt, Ch, Ma-Op, ZeSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

ALS2CR2 Antibody Summary

Immunogen
A portion of amino acids 200-250 of human Als2Cr2 was used as the immunogen for the antibody.
Predicted Species
Mouse (94%), Rat (94%), Chicken (94%), Zebrafish (90%), Opossum (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STRADB
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 2.0-4.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for ALS2CR2 Antibody

  • ALS2CR2candidate 2
  • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
  • CALS-21MGC102916
  • ILP-interacting protein
  • ILPIPSTRAD beta
  • Pseudokinase ALS2CR2
  • STE20-related kinase adaptor beta

Background

ALS2CR2 encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STRADB
Uniprot