Home » AlphaB Crystallin/CRYAB » AlphaB Crystallin/CRYAB Antibodies » AlphaB Crystallin/CRYAB [p Ser45] Antibody [Janelia Fluor® 669]
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AlphaB Crystallin/CRYAB [p Ser45] Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB120-5598AF350
Alexa Fluor 405
NB120-5598AF405
Alexa Fluor 488
NB120-5598AF488
Alexa Fluor 532
NB120-5598AF532
Alexa Fluor 594
NB120-5598AF594
Alexa Fluor 647
NB120-5598AF647
Alexa Fluor 700
NB120-5598AF700
Alexa Fluor 750
NB120-5598AF750
Allophycocyanin
NB120-5598APC
Biotin
NB120-5598B
CoraFluor 1
NB120-5598CL1
DyLight 350
NB120-5598UV
DyLight 405
NB120-5598V
DyLight 488
NB120-5598G
DyLight 550
NB120-5598R
DyLight 594
NB120-5598DL594
DyLight 650
NB120-5598C
DyLight 680
NB120-5598FR
DyLight 755
NB120-5598IR
FITC
NB120-5598F
HRP
NB120-5598H
Janelia Fluor 525
NB120-5598JF525
Janelia Fluor 549
NB120-5598JF549
Janelia Fluor 585
NB120-5598JF585
Janelia Fluor 635
NB120-5598JF635
Janelia Fluor 646
NB120-5598JF646
PE
NB120-5598PE
PerCP
NB120-5598PCP
Unconjugated
NB120-5598
mFluor Violet 450 SE
NB120-5598MFV450
mFluor Violet 500 SE
NB120-5598MFV500
mFluor Violet 610 SE
NB120-5598MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB120-5598
BSA Free
NB120-5598
BSA Free
NB120-5598-0.025mg
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AlphaB Crystallin/CRYAB [p Ser45] Antibody [Janelia Fluor® 669] Summary

Immunogen
Synthetic phopshopeptide corresponding to residues L(44) S(p) P F Y L R P P S F(54) C of human alpha-B Crystallin.
Modification
p Ser45
Localization
Cytoplasmic
Specificity
This does not detect the unphosphorylated form of the protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRYAB
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for AlphaB Crystallin/CRYAB [p Ser45] Antibody [Janelia Fluor® 669]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • CRYAB
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component

Background

Crystallin AB is a member of the small heat shock protein family and expressed in several tissues including brain, kidney cardiac and skeletal muscle. Crystallin AB functions as a molecular chaperone and in intracellular architecture. Crystallin AB has shown to have interactions with CRYAA, CRYGC, CRYBB2, CRYBA1 and HSPB8. Defects in crystalline AB have been linked to cause myopathy myofibrillar type 2, cataract posterior polar type 2, and myopathy myofibrillar fatal infantile hypertonic alpha-B crystallin-related (MFMFIH-CRYAB).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRYAB