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AlphaB Crystallin/CRYAB Antibody (CPTC-CRYAB-1) [DyLight 650]

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC, MA
Clone
CPTC-CRYAB-1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

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AlphaB Crystallin/CRYAB Antibody (CPTC-CRYAB-1) [DyLight 650] Summary

Immunogen
Recombinant human full-length AlphaB Crystallin/CRYAB protein (Uniprot: P02511)
Localization
Cytoplasm. Translocates to nucleus during heat shock and resides in nuclear splicing speckles.
Isotype
IgG2c Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CRYAB
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AlphaB Crystallin/CRYAB Antibody (CPTC-CRYAB-1) [DyLight 650]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • CRYAB
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component

Background

Crystallin AB is a member of the small heat shock protein family and expressed in several tissues including brain, kidney cardiac and skeletal muscle. Crystallin AB functions as a molecular chaperone and in intracellular architecture. Crystallin AB has shown to have interactions with CRYAA, CRYGC, CRYBB2, CRYBA1 and HSPB8. Defects in crystalline AB have been linked to cause myopathy myofibrillar type 2, cataract posterior polar type 2, and myopathy myofibrillar fatal infantile hypertonic alpha-B crystallin-related (MFMFIH-CRYAB).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol CRYAB