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Alpha Actinin 2 Antibody (ACTN2/3291) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
ACTN2/3291
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

Alpha Actinin 2 Antibody (ACTN2/3291) [Janelia Fluor® 646] Summary

Immunogen
A recombinant fragment (aa557-692) of human Alpha Actinin 2 protein (exact sequence is proprietary) (Uniprot: P35609)
Localization
Cytoplasmic
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ACTN2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Alpha Actinin 2 Antibody (ACTN2/3291) [Janelia Fluor® 646]

  • Actinin alpha 2
  • actinin, alpha 2
  • Actinin-a2
  • ACTN2
  • alpha Actinin 2
  • alpha-Actinin 2
  • Alpha-actinin skeletal muscle isoform 2
  • Alpha-Actinin Skeletal Muscle
  • Alpha-Actinin-2
  • CMD1AA
  • F-actin cross-linking protein

Background

Alpha actinin 2 is an actin binding proteins that carry out different purposes in different different cell types. Skeletal, cardiac, and smooth muscle isoforms are localized to the Z disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. There are several known transcript variants that result from the use of multiple polyA+ sites. ACTN2 has the ability to form both homo- and heterodimers (with ACTN3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ACTN2