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Adenylate Cyclase 8 Antibody (ADCY8/7341) - Azide and BSA Free

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Formalin-fixed, paraffin-embedded human kidney stained with Adenylate Cyclase 8 antibody (ADCY8/7341) - Azide and BSA Free. HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human kidney stained with Adenylate Cyclase 8 antibody (ADCY8/7341) - Azide and BSA Free. HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human brain stained with Adenylate Cyclase 8 antibody (ADCY8/7341) - Azide and BSA Free. Inset: PBS instead of primary antibody; secondary only negative control.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
ADCY8/7341
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-24064AF350
Alexa Fluor 405
NBP3-24064AF405
Alexa Fluor 488
NBP3-24064AF488
Alexa Fluor 532
NBP3-24064AF532
Alexa Fluor 594
NBP3-24064AF594
Alexa Fluor 647
NBP3-24064AF647
Alexa Fluor 700
NBP3-24064AF700
Alexa Fluor 750
NBP3-24064AF750
Allophycocyanin
NBP3-24064APC
Biotin
NBP3-24064B
CoraFluor 1
NBP3-24064CL1
DyLight 350
NBP3-24064UV
DyLight 405
NBP3-24064V
DyLight 488
NBP3-24064G
DyLight 550
NBP3-24064R
DyLight 594
NBP3-24064DL594
DyLight 650
NBP3-24064C
DyLight 680
NBP3-24064FR
DyLight 755
NBP3-24064IR
FITC
NBP3-24064F
HRP
NBP3-24064H
Janelia Fluor 525
NBP3-24064JF525
Janelia Fluor 549
NBP3-24064JF549
Janelia Fluor 585
NBP3-24064JF585
Janelia Fluor 635
NBP3-24064JF635
Janelia Fluor 646
NBP3-24064JF646
Janelia Fluor 669
NBP3-24064JF669
PE
NBP3-24064PE
PerCP
NBP3-24064PCP
Unconjugated
NBP3-23608-100ug
mFluor Violet 450 SE
NBP3-24064MFV450
mFluor Violet 500 SE
NBP3-24064MFV500
mFluor Violet 610 SE
NBP3-24064MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-23608-100ug
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Adenylate Cyclase 8 Antibody (ADCY8/7341) - Azide and BSA Free Summary

Description
Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant fragment (around aa1-200) of human Adenylate Cyclase 8 protein (exact sequence is proprietary)
Localization
Cell surface. Multi-pass membrane protein. Cytoplasm.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ADCY8
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
10mM PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Adenylate Cyclase 8 Antibody (ADCY8/7341) - Azide and BSA Free

  • AC8
  • ADCY3
  • ADCY8
  • adenylate cyclase 8 (brain)
  • Adenylate Cyclase 8
  • adenylate cyclase type 8
  • Adenylate cyclase type VIII
  • Adenylyl cyclase 8
  • adenylyl cyclase-8, brain
  • ATP pyrophosphate-lyase 8
  • Ca(2+)/calmodulin-activated adenylyl cyclase
  • EC 4.6.1.1
  • HBAC1

Background

ADCY8, also known as Adenylate cyclase type 8, is a 140 kDa 1,251 amino acid protein, and is involved in the encoding of a membrane-bound enzyme that has to do with learning. This protein has also been shown to have interactions with CALM1, CALM2, CALM3, PPP2CA, and CFTR in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY8 and drug dependence, bipolar disorder, cholera, and Alzheimer's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADCY8