Adenylate Cyclase 8 Antibody (ADCY8/7341) Summary
Description |
Store at 2 to 8C. Non-hazardous. No MSDS required. |
Immunogen |
Recombinant fragment (around aa1-200) of human Adenylate Cyclase 8 protein (exact sequence is proprietary) |
Localization |
Cell surface. Multi-pass membrane protein. Cytoplasm. |
Isotype |
IgG Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
ADCY8 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Paraffin 1-2ug/ml
|
Application Notes |
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C. |
Buffer |
10mM PBS with 0.05% BSA |
Preservative |
0.05% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for Adenylate Cyclase 8 Antibody (ADCY8/7341)
Background
ADCY8, also known as Adenylate cyclase type 8, is a 140 kDa 1,251 amino acid protein, and is involved in the encoding of a membrane-bound enzyme that has to do with learning. This protein has also been shown to have interactions with CALM1, CALM2, CALM3, PPP2CA, and CFTR in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY8 and drug dependence, bipolar disorder, cholera, and Alzheimer's disease.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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