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ADAM2 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining in human testis and liver tissues using anti-ADAM2 antibody. Corresponding ADAM2 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining of human testis shows high expression.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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ADAM2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NVSYGIEPLESSVGFEHVIYQVKHKKADVSLYNEKDIESRDLSFKLQSVEPQQDFAKYIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADAM2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
IHC reported in scientific literature (PMID: 26252478). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
ADAM2 Protein (NBP1-85416PEP)
Publications
Read Publication using
NBP1-85416 in the following applications:

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 26252478).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ADAM2 Antibody

  • ADAM metallopeptidase domain 2
  • ADAM2
  • Cancer/testis antigen 15
  • CRYN2
  • CT15
  • CT15ADAM 2
  • disintegrin and metalloproteinase domain-containing protein 2
  • EC 3.4.24
  • Fertilin beta
  • Fertilin subunit beta
  • FTNBCRYN1
  • PH30
  • PH-30
  • PH-30b
  • PH30-beta
  • PH30PH30-beta

Background

ADAM2, or Disintegrin and metalloproteinase domain-containing protein 2, contains a 82 kDa and a 80 kDa isoform, and is involved in the adhesion of the sperm-egg membrane during fertilization. Current research is being conducted to determine the relationship between ADAM2 and a variety of disorders and diseases, including infertility, epidiymitis, Alzheimer's disease, and reflex sympathetic dystrophy. ADAM2 has been linked to the integrin-mediated signaling pathway and processes involving cellular adhesion, through which it interacts with CD9, CLGN, CRYAB, DNM1, and ITGA9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ADAM2 Antibody (NBP1-85416)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


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IF/IHC
(1)
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Bioinformatics

Gene Symbol ADAM2