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Tick-borne Diseases: Disease Bioinformatics

Tick-borne diseases are transmitted through tick bites. It takes about 24 hours for the pathogen to travel from the saliva in the tick to the victim’s bloodstream. Common symptoms of tick-borne diseases include rash near the site of the tick bite, fever, headache, muscle ache, and fatigue. Severity of tick-borne diseases ranges, but most types can be treated by antibiotics. However, diagnosis of tick-borne diseases is difficult, and there are no vaccines available for most kinds of tick-borne diseases. To prevent tick-borne diseases, people should wear protective clothing in tick-infested areas, utilize insect repellant, and remove ticks within 24 hours of being bitten.

Top Research Reagents

We have 2032 products for the study of Tick-borne Diseases that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

C-Reactive Protein/CRP [HRP]
DCRP00B
N/A C-Reactive Protein/CRP [HRP]N/A C-Reactive Protein/CRP [HRP]


Species Human
Applications ELISA

150 Publications
PSMC6 Antibody (2C4)
H00005706-M02
Western Blot: PSMC6 Antibody (2C4) [H00005706-M02] - Analysis of PSMC6 expression in transfected 293T cell line by PSMC6 monoclonal antibody (M02), clone 2C4.Lane 1: PSMC6 transfected lysate(44.2 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: PSMC6 Antibody (2C4) [H00005706-M02] - Analysis of monoclonal antibody to PSMC6 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

RAIN Antibody
NBP3-35851
Western Blot: RAIN Antibody [NBP3-35851] - Western blot analysis of various lysates using RAIN Rabbit pAb at 1:1000 dilution.<br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 60s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

MAP1 Antibody (4A1)
H00064112-M02
Western Blot: MAP1 Antibody (4A1) [H00064112-M02] - Analysis of MOAP1 expression in transfected 293T cell line by MOAP1 monoclonal antibody (M02), clone 4A1.Lane 1: MOAP1 transfected lysate(39.5 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: MAP1 Antibody (4A1) [H00064112-M02] - Analysis of monoclonal antibody to MOAP1 on HeLa cell . Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
NCKIPSD Antibody
NBP1-42664
Western Blot: NCKIPSD Antibody [NBP1-42664] - Detection of Human SPIN90 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SPIN90 antibody NBP1-42664 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunohistochemistry: NCKIPSD Antibody [NBP1-42664] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- SPIN90 used at a dilution of 1:500 (0.4ug/ml). Detection: DAB. Counterstain: IHC Hematoxylin (blue).

Rabbit Polyclonal
Species Human
Applications WB, IHC, IP

PIAS2 Antibody
NBP1-52022
Western Blot: PIAS2 Antibody [NBP1-52022] - WB analysis of PIAS2 using anti-PIAS2 antibody on Jurkat cell lyste (30 ug cell lysate boiled in lysis buffer). Image from verified customer review. Western Blot: PIAS2 Antibody [NBP1-52022] - Western blot analysis of PIAS2 (aa185-196) in Human Peripheral Lymphocytes lysate (35ug protein in RIPA buffer) using NBP1-52022 at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Goat Polyclonal
Species Human
Applications WB, PEP-ELISA

     1 Review

1 Publication
HSP60 Antibody - BSA Free
NBP1-77397
Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - HeLa cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with HSP60 Antibody (NBP1-77397) at 1 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.Western Blot: HSP60 Antibody [NBP1-77397] - Analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     4 Reviews

6 Publications
FMN1 Antibody (4F4)
H00342184-M07
Western Blot: FMN1 Antibody (4F4) [H00342184-M07] - Analysis of FMN1 expression in Jurkat.Immunocytochemistry/Immunofluorescence: FMN1 Antibody (4F4) [H00342184-M07] - Analysis of monoclonal antibody to FMN1 on HeLa cell. Antibody concentration 10 ug/ml

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

WDR77 Antibody
NBP1-82778
Western Blot: WDR77 Antibody [NBP1-82778] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: WDR77 Antibody [NBP1-82778] - Staining of human cell line A-431 shows localization to nucleoplasm, cytosol & the Golgi apparatus. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

ERK1 Antibody (1E5) - BSA Free
NBP2-22203
Western Blot: ERK1 Antibody (1E5) [NBP2-22203] - Western blot analysis of whole cell lysates from (1) MCF7 (2) NIH3T3 cell lines using ERK1 antibody (clone 1E5) at 1:1000 dilution. The signal was developed using HRP labeled goat-anti Mouse secondary antibody with ECL based detection. Immunocytochemistry/Immunofluorescence: ERK1 Antibody (1E5) [NBP2-22203] - Analysis of NIH/3T3 cells using ERK1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

1 Publication
Signal Peptide Peptidase Antibody
NBP2-32276
Western Blot: Signal Peptide Peptidase Antibody [NBP2-32276] - Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-SPP antibody NBP2-32276 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunoprecipitation: Signal Peptide Peptidase Antibody [NBP2-32276] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-SPP antibody NBP2-32276 used for IP at 6 ug per reaction. SPP was also immunoprecipitated by rabbit anti-SPP antibody BL16569. For blotting immunoprecipitated SPP, NBP2-32276 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Rabbit Polyclonal
Species Human
Applications WB, IP

ERK2 Antibody [Unconjugated]
AF1230
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, MCF-7 human breast cancer cell line, U937 human histiocytic lymphoma cell line, PC-12 rat adrenal pheochromocytoma cell line, and NIH-3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 0.1 µg/mL of Rabbit Anti-Human/Mouse/Rat ERK2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1230) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <a class= ERK2 was detected in immersion fixed paraffin-embedded sections of human breast using Rabbit Anti-Human/Mouse/Rat ERK2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1230) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, KO

3 Publications
FoxC2 Antibody
AF6989
FoxC2 was detected in immersion fixed frozen sections of mouse embryo (E15.5) using Sheep Anti-Mouse FoxC2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6989) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=YAP and TAZ are required for the maintenance of LVs. The lymphatic vessels in the dorsal skin of E16.5 and E18.5 control and Lyve1-Cre;Yapf/f;Tazf/f embryos were analyzed by whole-mount immunohistochemistry. (A,B) LVs were observed in the collecting lymphatic vessels of E16.5 control and Lyve1-Cre;Yapf/f;Tazf/f embryos (arrows). (C,D) The migrating front of E16.5 control (C) and Lyve1-Cre;Yapf/f;Tazf/f (D) embryos appeared comparable. (E-G) At E18.5, the lymphatic vessels from the left and right sides have merged to form a network in control embryos (E). In contrast, huge gaps were observed in between the migrating fronts of E18.5 Lyve1-Cre;Yapf/f;Tazf/f embryos (F, magenta lines). The lymphatic vessels of mutant embryos were also dilated. The distance between the migrating fronts and the diameter of vessels are quantified in G. (H,I) LVs were observed in the collecting lymphatic vessels of E18.5 control embryos (H, yellow arrows). In contrast, the dilated lymphatic vessels of E18.5 Lyve1-Cre;Yapf/f;Tazf/f embryos lacked LVs (I). The various parameters of lymphatic vascular patterning were quantified and are plotted in G. n=4 embryos per each genotype. ****P<0.0001. Data are mean±s.e.m. Scale bars: 200 µm in A-D; 500 µm in E,F; 200 µm in H,I. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33060128), licensed under a CC-BY license. Not internally tested by R&D Systems.

Sheep Polyclonal
Species Mouse
Applications IHC

27 Publications
IL-4 [Unconjugated]
6507-IL/CF
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 0.05-0.2 ng/mL.


Species Human
Applications BA

3 Publications
GM-CSF [Unconjugated]
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
LAMC2 Antibody (CL2980)
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications
Alpha-parvin/Actopaxin Antibody (OTI1C10)
NBP2-46326
Western Blot: Alpha-parvin/Actopaxin Antibody (OTI1C10) [NBP2-46326] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Alpha-parvin.Immunohistochemistry: Alpha-parvin/Actopaxin Antibody (OTI1C10) [NBP2-46326] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

GTF2H2 Antibody (PCRP-GTF2H2-1B9)
NBP3-07348
Immunocytochemistry/Immunofluorescence: GTF2H2 Antibody (PCRP-GTF2H2-1B9) [NBP3-07348] - Immunofluorescence Analysis of PFA-fixed MCF7 cells. GTF2H2 Mouse Monoclonal Antibody (PCRP-GTF2H2-1B9) followed by goat anti- Mouse IgG-CF488 (green). Phalloidin counterstain (red).Flow Cytometry: GTF2H2 Antibody (PCRP-GTF2H2-1B9) [NBP3-07348] - Flow Cytometric Analysis of PFA-fixed HeLa cells. GTF2H2 Mouse Monoclonal Antibody (PCRP-GTF2H2-1B9) followed by goat anti- Mouse IgG-CF488 (blue); unstained cells (red).

Mouse Monoclonal
Species Human
Applications Flow, ICC/IF, PA

Recombinant Human IFI44 GST (N-Term) Protein
H00010561-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA


Related Genes

Tick-borne Diseases has been researched against:

Related Pathways

Tick-borne Diseases has been linked to:

Related Diseases

Tick-borne Diseases has been studied in relation to diseases such as:

Related PTMs

Tick-borne Diseases has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Tick-borne Diseases is also known as Disease Transmitted By Tick, Disease, Tick-borne, Diseases, Tick-borne, Tick Borne Diseases, Tick-borne Disease.