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Pyrophosphate Arthritis: Disease Bioinformatics

Research of Pyrophosphate Arthritis has been linked to Arthropathy, Calcium Pyrophosphate Deposition Disease, Arthritis, Degenerative Polyarthritis, Rheumatoid Arthritis. The study of Pyrophosphate Arthritis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Pyrophosphate Arthritis include Pathogenesis, Osteoclast Differentiation, Aging, Bone Resorption, Inflammatory Response. These pathways complement our catalog of research reagents for the study of Pyrophosphate Arthritis including antibodies and ELISA kits against AGGRECANASE, ACP5, ACAN, C3, CAPG.

Top Research Reagents

We have 3420 products for the study of Pyrophosphate Arthritis that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

TRAF-2 Antibody
NB100-56173
Western Blot: TRAF-2 Antibody [NB100-56173] - Analysis of TRAF-2 in normal human tissues using this antibody. TRAF-2 is observed at ~60-64 kDa. Additional bands of lower molecular weight were seen in some cases, and may represent TRAF-2 degradation fragments.Immunocytochemistry/Immunofluorescence: TRAF-2 Antibody [NB100-56173] - Immunostaining of HN30 and MCF-12a cells for TRAF2 3 days post-transfectionMCF-12a NT (DAPI): non-treated MCF-12a DAPI stained, MCF-12a NT (TRAF2-FITC): non-treated MCF-12a FITC stained for TRAF2, MCF-12a pNSP 5a3a (DAPI): MCF-12a transfected with pcDNA 3.0 NSP 5a3a DAPI stained, MCF-12a pNSP 5a3a (TRAF2-FITC): MCF-12a transfected with pcDNA 3.0 NSP 5a3a FITC stained for Traf-2, HN30 NT (DAPI): non-treated HN30 DAPI stained, HN30 NT (TRAF2-FITC): non-treated HN30 FITC stained for TRAF2, HN30 pNSP 5a3a (DAPI): HN30 transfected with pcDNA 3.0 NSP 5a3a DAPI stained, HN30 pNSP 5a3a (TRAF2-FITC): HN30 transfected with pcDNA 3.0 NSP 5a3a FITC stained for TRAF2. White arrows indicate apoptotic bodies. Image collected and cropped by Citeab from the following publication (A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. Oncotarget (2011) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human
Applications WB, Flow, ICC/IF

4 Publications
TRACP/PAP/ACP5 Antibody - Azide and BSA Free
H00000054-D01P
Western Blot: ACP5 Antibody [H00000054-D01P] - Analysis of ACP5 expression in human liver.Western Blot: ACP5 Antibody [H00000054-D01P] - Analysis of ACP5 expression in transfected 293T cell line by ACP5 polyclonal antibody.Lane 1: ACP5 transfected lysate(36.60 KDa).Lane 2: Non-transfected lysate.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

3 Publications
Aggrecan Neoepitope Antibody - BSA Free
NB100-74350
Western Blot: Aggrecan Neoepitope Antibody [NB100-74350] - Analysis of ACAN in L929 whole cell extract using NB100-74350.Immunocytochemistry/Immunofluorescence: Aggrecan Neoepitope Antibody [NB100-74350] - Detection of ACAN in OA cartilage using NB100-74350.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

32 Publications
SCYL1 Antibody (2E5) - Azide and BSA Free
H00057410-M02
Western Blot: SCYL1 Antibody (2E5) [H00057410-M02] - SCYL1 monoclonal antibody (M02), clone 2E5. Analysis of SCYL1 expression in NIH/3T3.Western Blot: SCYL1 Antibody (2E5) [H00057410-M02] - SCYL1 monoclonal antibody (M02), clone 2E5. Analysis of SCYL1 expression in PC-12.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, S-ELISA

1 Publication
OXSM Antibody - BSA Free
NBP1-84732
Western Blot: OXSM Antibody [NBP1-84732] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunohistochemistry-Paraffin: OXSM Antibody [NBP1-84732] - Staining of human lymph node.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

TDRD7 Antibody - BSA Free
NBP1-87315
Immunohistochemistry: TDRD7 Antibody [NBP1-87315] - Staining of human testis shows cytoplasmic and nuclear positivity in subsets of testicular cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

1 Publication
CapG Antibody - BSA Free
NBP1-90214
Immunohistochemistry-Paraffin: CapG Antibody [NBP1-90214] - Analysis in human lung and liver tissues. Corresponding CAPG RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: CapG Antibody [NBP1-90214] - Staining of human lung, lymph node, skeletal muscle and small intestine using Anti-CAPG antibody (A) NBP1-90214 shows similar protein distribution across tissues to independent antibody NBP1-90215 (B).

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Complement Component C3d Antibody [Unconjugated]
AF2655
Complement Component C3d was detected in perfusion fixed frozen sections of mouse kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href= Complement Component C3d was detected in perfusion fixed paraffin-embedded sections of rat kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, IHC

61 Publications
CD46 Antibody (344519) [Unconjugated]
MAB2005
PBMC lymphocytes were stained with Mouse Anti-Human CD46 Monoclonal Antibody (Catalog # MAB2005, filled histogram) or isotype control antibody (Catalog # <a class=NoLineLink href=

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

     1 Review

3 Publications
COMP/Thrombospondin-5 [HRP]
DCMP0
N/A COMP/Thrombospondin-5 [HRP]N/A COMP/Thrombospondin-5 [HRP]


Species Human
Applications ELISA

12 Publications
Vitronectin [Unconjugated]
2308-VN


Species Human
Applications BA

11 Publications
Osteoprotegerin/TNFRSF11B [Biotin]
DY805
N/A Osteoprotegerin/TNFRSF11B [Biotin]


Species Human
Applications ELISA

90 Publications
TIMP-1 [HRP]
DTM100
N/A TIMP-1 [HRP]N/A TIMP-1 [HRP]


Species Human
Applications ELISA

97 Publications
MMP-3 [HRP]
DMP300
N/A MMP-3 [HRP]N/A MMP-3 [HRP]


Species Human
Applications ELISA

55 Publications
CD40 Ligand/TNFSF5 [HRP]
DCDL40
N/A CD40 Ligand/TNFSF5 [HRP]N/A CD40 Ligand/TNFSF5 [HRP]


Species Human
Applications ELISA

44 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

824 Publications
TRANCE/TNFSF11/RANK L [Unconjugated]
462-TEC
Recombinant Mouse TRANCE/TNFSF11/RANK L (Catalog # 462-TEC) induces osteoclast differentiation of the RAW 264.7 mouse monocyte/macrophage cell line. The ED<SUB>50</SUB> for this effect is 0.5-2 ng/mL. 1 μg/lane of Recombinant Mouse TRANCE/TNFSF11/RANK L was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 19 kDa.


Species Mouse
Applications BA

92 Publications
Endostatin [HRP]
DNST0
N/A Endostatin [HRP]N/A Endostatin [HRP]


Species Human
Applications ELISA

22 Publications
RANK/TNFRSF11A Antibody (9A725) - BSA Free
NB100-56508
Western Blot: RANK/TNFRSF11A Antibody (9A725) [NB100-56508] - Analysis of RANK in transfected 293 cells using RANK antibody at 2 ug/ml.Flow Cytometry: RANK/TNFRSF11A Antibody (9A725) - BSA Free [NB100-56508] - An intracellular stain was performed on Raw264.7 cells with RANK/TNFRSF11A Antibody (9A725) NB100-56508 (blue) and a matched isotype control MAB002 (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Dylight 550 (84540, Thermo Fisher).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

19 Publications

Related Genes

Pyrophosphate Arthritis has been researched against:

Related Pathways

Pyrophosphate Arthritis has been linked to:

Related Diseases

Pyrophosphate Arthritis has been studied in relation to diseases such as:

Related PTMs

Pyrophosphate Arthritis has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Pyrophosphate Arthritis is also known as Pyrophosphate Arthropathy.