DGAT1 Products

Description

Diglyceride acyltransferase (DGAT) is a membrane-bound Sterol o-acyltransferase subfamily member. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. Specifically, it catalyzes the terminal step in triacylglycerol synthesis, using diacylglycerol (DAG) and fatty acyl CoA as substrates.

DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.

Bioinformatics

Entrez	13350 Mouse 84497 Rat 8694 Human
Uniprot	O75907 Human
Product By Gene ID	8694
Alternate Names	ACAT-related gene product 1 AGRP1 ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1 DGATACAT related gene product 1 diacylglycerol O-acyltransferase 1 diacylglycerol O-acyltransferase homolog 1 (mouse) diacylglycerol O-acyltransferase homolog 1 Diglyceride acyltransferase EC 2.3.1 EC 2.3.1.20

Research Areas for DGAT1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research
Lipid and Metabolism
Lipid Droplets
Signal Transduction

Related DGAT1 Blog Posts

Check out the latest blog posts on DGAT1.

Can you DGAT? DGAT1 & DGAT2 Antibodies for Metabolic Pathway Research Triacylglycerols (triglycerides) (TGs) are the major storage molecules of metabolic energy and FAs in most living organisms. Excessive accumulation of TGs, however, is associated with human diseases, such as obesity, diabetes mellitus, and steatohepat...    Read more.

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