TOR/mTOR Products

Description

The mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase which helps to mediate many cellular processes. Specifically, mTOR is invloved in the cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex, making mTOR antibodies useful tools for a number of important research areas.

Bioinformatics

Entrez	2475 Human 56717 Mouse 56718 Rat
Uniprot	NM_004958 Human NP_004949 Human NP_004949.1 Human P42345 Human
Product By Gene ID	2475
Alternate Names	EC 2.7.11.1 FK506 binding protein 12-rapamycin associated protein 1 FK506 binding protein 12-rapamycin associated protein 2 FK506-binding protein 12-rapamycin complex-associated protein 1 FKBP12-rapamycin complex-associated protein FLJ44809 FRAP FRAP1FKBP12-rapamycin complex-associated protein 1 FRAP2 Mammalian target of rapamycin mechanistic target of rapamycin (serine/threonine kinase) Mechanistic target of rapamycin mTOR RAFT1 rapamycin and FKBP12 target 1 rapamycin associated protein FRAP2 Rapamycin target protein 1 RAPT1FKBP-rapamycin associated protein serine/threonine-protein kinase mTOR

Research Areas for TOR/mTOR

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Cell Cycle and Replication
DNA Repair
Hypoxia
MAP Kinase Signaling
mTOR Pathway
Phospho-Specific
Signal Transduction
Translation Control

Related TOR/mTOR Blog Posts

Check out the latest blog posts on TOR/mTOR.

Thomson Reuters Predicts 2016 Nobel Prize Winners Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call fro...    Read more.

The Many Connections Between Autophagy and Kidney Disease By Yoskaly Lazo-Fernandez, PhD The first description of what is called today an autophagosome was given in a paper published in 1957. Its author employed electron microscopy to observe the neonatal features of mous...    Read more.

mTOR Signaling and the Tumor Microenvironment By Yoskaly Lazo-Fernandez, PhD The mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that, as a member of two distinct intracellular protein complexes, mTORC1 and mTORC2, regulates protein ...    Read more.

mTOR - a central regulator of cell metabolism The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein comp...    Read more.

Staufen1 Overabundance and the Consequent mTOR Hyperactivity in Amyotrophic Lateral Sclerosis, Spinocerebellar Ataxia Type 2, Alzheimer’s, Parkinson’s, and Huntington’s Diseases Jamshed Arslan, Pharm D, PhD Neurodegenerative disorders involve loss of function and, ultimately, death of neurons. Selective neuronal vulnerability has been observed in a variety of neurodegenerative diseases. Fo...    Read more.

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