KRAS Products

Description

KRAS, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Bioinformatics

Entrez	3845 Human
Uniprot	AAH13572 Human NM_004985 Human NP_004976 Human P01111 Human P01116 Human
Product By Gene ID	3845
Alternate Names	cellular c-Ki-ras2 proto-oncogene c-Ki-ras c-K-ras C-K-RAS GTPase KRas Ki-Ras KI-RAS Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog K-Ras 2 K-ras p21 protein KRAS1 K-RAS2A K-RAS2B KRAS2NS3 K-RAS4A K-RAS4B NS oncogene KRAS2 PR310 c-K-ras oncogene RASK2c-Kirsten-ras protein transforming protein p21 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Research Areas for KRAS

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Core ESC-Like Genes
mTOR Pathway
Stem Cell Markers

Related KRAS Blog Posts

Check out the latest blog posts on KRAS.

Autophagy: Pro or Anti-tumorigenic? And the role of epigenetics in this debate By Christina Towers, PhDAutophagy is an evolutionarily conserved process that cells use to break down damaged cytoplasmic constituents in order to fuel cellular metabolism, particularly in instances of stress. This process has been heavily ...    Read more.

Understanding ‘Y’ in Breast Cancer: Crucial Role of DNA/RNA-binding Protein YB-1 in the Development, Pre-Invasive, and Metastatic Phases Jamshed Arslan, Pharm D, PhD In the United States, 1 in 8 women will be diagnosed with breast cancer in her lifetime.1 Despite the prevalence, cancer genesis is a mystery. The heterogeneity of cancers makes it diff...    Read more.

Read more KRAS related blogs.