ACAT1 Products

Description

Sterol O-acyltransferase 1 (SOAT1), also known as ACAT1, catalyzes the formation of intracellular cholesterol esters in various tissues, such as adult human liver, adrenal glands, macrophages, and kidneys. Specifically, ACAT-1 catalyzes the reversible reaction forming acetoacetyl-CoA from two molecules of acetyl-CoA. Additionaly, the ACAT 1 protein may have a role in lipoprotein assembly and dietary cholesterol absorption, and may also act as a ligase.

Mutations in this gene have been associated with 3-ketothiolase deficiency, an inborn defect of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Bioinformatics

Entrez	110446 Mouse 25014 Rat 38 Human
Uniprot	AAH10942 Human NP_000010 Human NP_000010.1 Human P24752 Human P35610 Human
Product By Gene ID	38
Alternate Names	ACAT acetoacetyl Coenzyme A thiolase Acetoacetyl-CoA thiolase acetyl-CoA acetyltransferase 1 acetyl-CoA acetyltransferase, mitochondrial acetyl-Coenzyme A acetyltransferase 1 EC 2.3.1 EC 2.3.1.9 MAT mitochondrial acetoacetyl-CoA thiolase T2 THIL

Research Areas for ACAT1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Lipid and Metabolism
Mitochondrial Markers
Signal Transduction