Species: Hu, Mu, Po
Applications: WB, ICC/IF, IHC, MS
Host: Rabbit Polyclonal
Species: All-Multi
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Eq
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.
Bioinformatics
| Entrez |
Mouse
Rat
Human
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
7040 |
| Alternate Names |
- CEDLAP
- DPD1
- latency-associated peptide
- TGF beta
- TGFB
- TGF-beta 1 protein
- TGFbeta
- TGF-beta-1
- transforming growth factor beta-1
- transforming growth factor, beta 1
|
![Sandwich ELISA TGF-beta 1 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/TGF-beta-1-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79297-img0002.jpg)
![N/A TGF-beta 1 [HRP]](http://images.novusbio.com/fullsize/elisa/db100c_human-tgf-beta-1-quantikine-sixpak-6-plates-98202194716.jpg)
![N/A TGF-beta 1 [HRP]](http://images.novusbio.com/fullsize/elisa/db100c_human-tgf-beta-1-quantikine-sixpak-6-plates-98202194825.jpg)
![N/A TGF-beta 1 [HRP]](http://images.novusbio.com/fullsize/elisa/db100c_human-tgf-beta-1-quantikine-sixpak-6-plates-98202194957.jpg)
![N/A TGF-beta 1 [Biotin]](http://images.novusbio.com/fullsize2/DATA_TGFbeta_1_DY240_ELISA_2311.jpg)
![N/A TGF-beta 1 [Biotin]](http://images.novusbio.com/fullsize2/DATA_TGFbeta_1_DY1679_ELISA_1697.jpg)
![Bioactivity TGF-beta 1 [Unconjugated]](http://images.novusbio.com/fullsize/protein/7754-bhcf_recombinant-human-tgf-beta-1-human-cell-expressed-cf-bioactivity-1811202013946.jpg)
![Bioactivity TGF-beta 1 [Unconjugated]](http://images.novusbio.com/fullsize/protein/7754-bh_recombinant-human-tgf-beta-1-human-cell-expressed-protein-bioactivity-1811202092840.jpg)
![Bioactivity TGF-beta 1 [Unconjugated]](http://images.novusbio.com/fullsize/240-b_recombinant-human-tgf-beta-1-protein-bioactivity-1442023144939.jpg)