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Noggin Proteins

We offer Noggin Peptides and Noggin Proteins for use in common research applications: ELISA, Functional, Protein Array, SDS-Page, Western Blot. Each Noggin Peptide and Noggin Protein is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our Noggin Peptides and Noggin Proteins can be used in a variety of model species: Human, Mouse. Use the list below to choose the Noggin Peptide and Noggin Protein which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our Noggin Peptides and Proteins.
Alternate Names for Noggin Proteins
Noggin protein, NOG protein, SYM1 protein, symphalangism 1 (proximal) protein, synostoses (multiple) syndrome 1 protein, SYNS1 protein
13 Results for "noggin" in Peptides and Proteins
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6057-NG

Recombinant Human Noggin Protein

(196 Publications)
25 μg
6057-NG
Recombinant human Noggin (Catalog # 6057-NG) has a molecular weight (MW) of 58.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 6057-NG-025/CF
Carrier Free 6057-NG-100/CF
Carrier Free 6057-NG-01M/CF
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6057-NG/CF

Recombinant Human Noggin Protein, CF

(185 Publications)
25 μg
6057-NG/CF
BG01V human embryonic stem cells were cultured in Mouse Embryonic Fibroblast Conditioned Media supplemented with FGF basic (5 ng/mL). Stem cells were driven into early cells of the neuroectoderm using a 3 day incubation in recombinant human Noggin (25 µg/mL) from either R&D Systems (Lot 1, Lot 2; Catalog # 6057-NG) or from two separate competitors (Competitor 1, Competitor 2). Control cells were not incubated in Noggin (No Noggin). The cells were stained for the early ectoderm marker, Otx2, and the neuroectoderm marker, SOX1. (A) Representative images of SOX1 (green), Otx2 (red), and DAPI (blue) staining in embryonic stem cells differentiated with Noggin from R&D Systems or Noggin from Competitor 2. (B) SOX1+ clusters were quantified under each of the indicated culture conditions. Cells treated with R&D Systems Noggin showed an increase in SOX1+ cells compared to both untreated and competitor-treated cells. R&D Systems Noggin showed consistent differentiation across the lots tested. BG01V human embryonic stem cells are licensed from ViaCyte, Inc.
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 6057-NG-100/CF
Carrier Free 6057-NG-01M/CF
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6997-NG/CF

Recombinant Mouse Noggin (aa 28-232) Protein, CF

25 μg
6997-NG/CF
Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.04-0.16 μg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4 (314-BP).
Mu
Species Glossary
Reactivity: Mu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 6997-NG-100/CF
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6997-NG

Recombinant Mouse Noggin (aa 28-232) Protein

(1 Publication)
25 μg
6997-NG
Recombinant Mouse Noggin Protein (Catalog # 6997-NG) has a molecular weight (MW) of 55.7 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).
Mu
Species Glossary
Reactivity: Mu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 6997-NG-025/CF
Carrier Free 6997-NG-100/CF
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1967-NG

Recombinant Mouse Noggin Protein

(86 Publications)
25 μg
1967-NG
Recombinant mouse Noggin (1967-NG) inhibits recombinant human BMP-4-induced alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of recombinant human BMP-4 (314-BP).
Mu
Species Glossary
Reactivity: Mu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 1967-NG-025/CF
Carrier Free 1967-NG-100/CF
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3344-NG

Recombinant Human Noggin Fc Chimera Protein, CF

(24 Publications)
50 μg
3344-NG
Recombinant human Noggin Fc chimera (3344-NG) inhibits recombinant human BMP-4-induced alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 0.1-0.4 µg/mL in the presence of 30 ng/mL of recombinant human BMP-4 (314-BP).
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 3344-NG-500
Carrier Free 3344-NG-100
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719-NG

Recombinant Mouse Noggin Fc Chimera Protein, CF

(19 Publications)
50 μg
719-NG
Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.06-0.3 µg/mL in the presence of 30 ng/mL of Recombinant Human BMP-4 (314-BP).
Mu
Species Glossary
Reactivity: Mu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free 719-NG-010
Carrier Free 719-NG-100
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NBP2-35079

Recombinant Human Noggin Protein

(2 Publications)
5μg
NBP2-35079
SDS-Page: Recombinant Human Noggin Protein [NBP2-35079] - man Noggin Protein [NBP2-35079]
Hu
Species Glossary
Reactivity: Hu
PAGE, Bioactivity
Applications: PAGE, Bioactivity
Sample Size Available
Sizes: Sample Size Available
Available Formulations
Formulation Catalog # Availability Price  
Carrier-Free NBP2-35079-1mg
Carrier-Free NBP2-35079-100ug
Carrier-Free NBP2-35079-500ug
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NBP2-35098

Recombinant Mouse Noggin Protein

(1 Publication)
5μg
NBP2-35098
SDS-Page: Mouse Noggin Protein [NBP2-35098]
Mu
Species Glossary
Reactivity: Mu
PAGE, Bioactivity
Applications: PAGE, Bioactivity
Sample Size Available
Sizes: Sample Size Available
Available Formulations
Formulation Catalog # Availability Price  
Carrier-Free NBP2-35098-1mg
Carrier-Free NBP2-35098-100ug
Carrier-Free NBP2-35098-500ug
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Qk033

Recombinant Mouse/Rat Noggin, Animal-Free Protein

50 μg
Qk033
Noggin is a BMP inhibitor and its activity is determined by inhibition of BMP2 (Qk007) activity in a BMP-2 responsive firefly luciferase reporter assay.HEK293T cells are treated (in triplicate) with a serial dilution of Noggin and standard concentration of BMP2 for 6 hours. Firefly luciferase activity is measured and normalized to the control Renilla luciferase activity. EC50 = 62.7 ng/ml (1.4 nM).
Mu, Rt
Species Glossary
Reactivity: Mu, Rt
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free Qk033-0500
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Qk034

Recombinant Human Noggin, Animal-Free Protein

50 μg
Qk034
Human Noggin is a BMP inhibitor, and its activity is determined by inhibition of BMP2 (Qk007) activity in a BMP-2 responsive firefly luciferase reporter assay. HEK293T cells are treated in triplicate with a serial dilution of Noggin and a standard concentration of BMP2 for 6 hours. Firefly luciferase activity is measured and normalized to the control Renilla luciferase activity.EC50 = 70.1 ng/ml (1.5 nM).
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Available Formulations
Formulation Catalog # Availability Price  
Carrier Free Qk034-0500
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NBP3-07104

Recombinant Human Noggin Protein

5 μg
Hu
Species Glossary
Reactivity: Hu
Bioactivity
Applications: Bioactivity
Sample Size Available
Sizes: Sample Size Available
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