UGT1A9 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using H00054600-B01P	Applications	Species
Wang H, Bian T, Jin T et al. Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers. Pharmacogenomics. 2014-04-01 [PMID: 24897286]
Hardwick RN, Ferreira DW, More VR et al. Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease. Drug Metab Dispos. 2012-12-07 [PMID: 23223517]
Wen X, Donepudi AC, Thomas PE et al. Regulation of hepatic phase II metabolism in pregnant mice. J Pharmacol Exp Ther. 2013-01-01 [PMID: 23055538] (WB, Mouse)	WB	Mouse

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	WB	Mouse	03/16/2021	View Summary Application Western Blot Sample Tested Hepa 1-6 mouse hepatoma cell line Species Mouse Lot JB141 Comments Comments Blocking step: Milk as blocking agent for 1 hour; Concentration 5 %; Temperature 25°C 1st Ab Incubation time: 16 hours, Temperature 4°C; Diluent: 1% skim milk in TBST

Array H00054600-B01P

• UGT1A9 Antibodies
• UGT1A9 Lysate
• UGT1A9 Protein