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TMEFF2/Tomoregulin-2 Antibody (Janssen patent anti-TMEFF2) - Humanized

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
Janssen patent anti-TMEFF2
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-27983AF350
Alexa Fluor 405
NBP3-27983AF405
Alexa Fluor 488
NBP3-27983AF488
Alexa Fluor 532
NBP3-27983AF532
Alexa Fluor 594
NBP3-27983AF594
Alexa Fluor 647
NBP3-27983AF647
Alexa Fluor 700
NBP3-27983AF700
Alexa Fluor 750
NBP3-27983AF750
Allophycocyanin
NBP3-27983APC
Biotin
NBP3-27983B
CoraFluor 1
NBP3-27983CL1
DyLight 350
NBP3-27983UV
DyLight 405
NBP3-27983V
DyLight 488
NBP3-27983G
DyLight 550
NBP3-27983R
DyLight 594
NBP3-27983DL594
DyLight 650
NBP3-27983C
DyLight 680
NBP3-27983FR
DyLight 755
NBP3-27983IR
FITC
NBP3-27983F
HRP
NBP3-27983H
Janelia Fluor 525
NBP3-27983JF525
Janelia Fluor 549
NBP3-27983JF549
Janelia Fluor 646
NBP3-27983JF646
Janelia Fluor 669
NBP3-27983JF669
PE
NBP3-27983PE
PerCP
NBP3-27983PCP
mFluor Violet 450 SE
NBP3-27983MFV450
mFluor Violet 500 SE
NBP3-27983MFV500
mFluor Violet 610 SE
NBP3-27983MFV610
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TMEFF2/Tomoregulin-2 Antibody (Janssen patent anti-TMEFF2) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
TMEFF2
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
TMEFF2
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for TMEFF2/Tomoregulin-2 Antibody (Janssen patent anti-TMEFF2) - Humanized

  • CT120.2
  • HPP1member 2
  • Hyperplastic polyposis protein 1
  • TENB2
  • TMEFF2
  • Tomoregulin2
  • Tomoregulin-2
  • TPEFtomoregulin
  • TR-2
  • transmembrane protein TENB2
  • transmembrane protein with EGF-like and two follistatin-like domains 2
  • Transmembrane protein with EGF-like and two follistatin-like domains
  • TRtomoregulin-2

Background

TMEFF2(transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region. Clone J4B6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TMEFF2 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: CyTOF-ready, ICC, IHC, ICFlow

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Bioinformatics

Gene Symbol TMEFF2
Uniprot