Home » TIMP-2 » TIMP-2 Proteins » Recombinant Human TIMP-2 His Protein
Novus Biologicals products are now on bio-techne.com

Recombinant Human TIMP-2 His Protein

 (1 Publication)
 See All Related
Submit a Review

Images

 
(
Enlarge)
SDS-Page: Recombinant Human TIMP-2 Protein [NBP2-22869]
SDS-Page: Recombinant Human TIMP-2 Protein [NBP2-22869]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Recombinant Human TIMP-2 His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 27-220 of Human TIMP-2

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCS CSPVHPQQAF CNADVVIRAK AVSEKEVDSG NDIYGNPIKR IQYEIKQIKM FKGPEKDIEF IYTAPSSAVC GVSLDVGGKK EYLIAGKAEG DGKMHITLCD FIVPWDTLST TQKKSLNHRY QMGCECKITR CPMIPCYISS PDECLWMDWV TEKNINGHQA KFFACIKRSD GSCAWYRGAA PPKQEFLDIE DP
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
TIMP2
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
26.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP2-22869.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>85%, by SDS-PAGE

Alternate Names for Recombinant Human TIMP-2 His Protein

  • CSC-21Ktissue inhibitor of metalloproteinase 2
  • metalloproteinase inhibitor 2
  • TIMP metallopeptidase inhibitor 2
  • TIMP2
  • TIMP-2
  • Tissue inhibitor of metalloproteinases 2

Background

TIMP2 is a natural inhibitor of the matrix metalloproteinases, a group of peptidases involved in of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, this protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular. Recombinant human TIMP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

TIMP-1 [HRP]
DTM100
N/A TIMP-1 [HRP]
N/A TIMP-1 [HRP]
(97 Publications)
Species: Hu
Applications: ELISA
MMP-2 [HRP]
MMP200
N/A MMP-2 [HRP]
N/A MMP-2 [HRP]
(101 Publications)
Species: Ca, Hu, Mu, Po, Rt
Applications: ELISA
MMP-9 [HRP]
DMP900
N/A MMP-9 [HRP]
N/A MMP-9 [HRP]
(220 Publications)
Species: Hu
Applications: ELISA
MMP-14/MT1-MMP
Antibody (128527) [Un ...
MAB9181
Flow Cytometry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
Immunohistochemistry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
(11 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, IP, WB
MMP-3 [HRP]
DMP300
N/A MMP-3 [HRP]
N/A MMP-3 [HRP]
(53 Publications)
Species: Hu
Applications: ELISA
TIMP-3
[Unconjugated]
973-TM
TIMP-3 [Unconjugated]
(27 Publications)
Species: Hu
Applications: InhibAct
MMP-1 Antibody
(36665) [Unconjugated
MAB901
Knockout Validated MMP-1 Antibody (36665) [Unconjugated]
Immunohistochemistry MMP-1 Antibody (36665) [Unconjugated]
Immunohistochemistry MMP-1 Antibody (36665) [Unconjugated]
(40 Publications)
Species: Hu
Applications: IHC, IP, KO, Neut, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(817 Publications)
Species: Hu
Applications: BA
VEGF [HRP]
DVE00
N/A VEGF [HRP]
N/A VEGF [HRP]
N/A VEGF [HRP]
(684 Publications)
Species: Hu
Applications: ELISA
MMP-13 [HRP]
DM1300
N/A MMP-13 [HRP]
N/A MMP-13 [HRP]
(34 Publications)
Species: Hu
Applications: ELISA
MMP-7 [HRP]
DMP700
N/A MMP-7 [HRP]
N/A MMP-7 [HRP]
(39 Publications)
Species: Hu
Applications: ELISA
u-Plasminogen
Activator/Urokinase [ ...
1310-SE
Enzyme Activity u-Plasminogen Activator/Urokinase [Unconjugated]
(14 Publications)
Species: Hu
Applications: EnzAct
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(663 Publications)
Species: Mu
Applications: ELISA
Serpin E1/PAI-1
Antibody - BSA Free
NBP1-19773
Western Blot Serpin E1/PAI-1 Antibody - BSA Free
Immunocytochemistry/ Immunofluorescence Serpin E1/PAI-1 Antibody - BSA Free
Immunohistochemistry-Paraffin Serpin E1/PAI-1 Antibody - BSA Free
(2 Reviews)
(32 Publications)
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
MMP-8
908-MP
MMP-8
(10 Publications)
Species: Hu
Applications: EnzAct
TIMP-4 [HRP]
DTM400
N/A TIMP-4 [HRP]
N/A TIMP-4 [HRP]
N/A TIMP-4 [HRP]
(5 Publications)
Species: Hu
Applications: ELISA

Publications for TIMP-2 Recombinant Protein (NBP2-22869)(1)


Reviews for TIMP-2 Recombinant Protein (NBP2-22869) (0)

There are no reviews for TIMP-2 Recombinant Protein (NBP2-22869). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for TIMP-2 Recombinant Protein (NBP2-22869) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional TIMP-2 Products

Research Areas for TIMP-2 Recombinant Protein (NBP2-22869)

Find related products by research area.

Blogs on TIMP-2.

Check out the latest blog posts on TIMP-2.
Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation
By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.
TNF-alpha [Unconjugated]
210-TA-005

Contact Information

Product PDFs

  PDF Datasheet
  Request CofA
  Request SDS

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human TIMP-2 His Protein and receive a gift card or discount.


Bioinformatics

Gene Symbol TIMP2