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Tie-2 Antibody (83715) [PE/Cy5.5]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
83715
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3131U-100UG
Alexa Fluor 405
FAB3131V-100UG
Alexa Fluor 488
FAB3131G
Alexa Fluor 532
FAB3131X
Alexa Fluor 594
FAB3131T-100UG
Alexa Fluor 647
FAB3131R-100UG
Alexa Fluor 700
FAB3131N-100UG
Alexa Fluor 750
FAB3131S-100UG
Allophycocyanin
FAB3131A
Allophycocyanin/Cy7
FAB3131APCCY7
Biotin
FAB3131B
CoraFluor 1
FAB3131CL1
DyLight 350
FAB3131D
DyLight 405
FAB3131E
DyLight 488
FAB3131K
DyLight 550
FAB3131L
DyLight 594
FAB3131M
DyLight 650
FAB3131W
DyLight 680
FAB3131Y
DyLight 755
FAB3131Z
FITC
FAB3131F
HRP
FAB3131H
Janelia Fluor 525
FAB3131JF525
Janelia Fluor 549
FAB3131I
Janelia Fluor 585
FAB3131JF585
Janelia Fluor 635
FAB3131JF635
Janelia Fluor 646
FAB3131J
Janelia Fluor 669
FAB3131JF669
PE/Atto594
FAB3131PEATT594
PE/Cy7
FAB3131PECY7
PerCP
FAB3131C
Phycoerythrin
FAB3131P
Unconjugated
MAB3131-100
mFluor Violet 450 SE
FAB3131MFV450
mFluor Violet 500 SE
FAB3131MFV500
mFluor Violet 610 SE
FAB3131MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3131-100
Carrier Free
FAB3131N-100UG
Carrier Free
FAB3131P
Carrier Free
FAB3131A
Carrier Free
FAB3131G
Carrier Free
MAB3131-SP
Carrier Free
MAB3131-500
Carrier Free
MAB3131-100
Carrier Free
FAB3131V-100UG
Carrier Free
FAB3131U-100UG
Carrier Free
FAB3131T-100UG
Carrier Free
FAB3131S-100UG
Carrier Free
FAB3131R-100UG
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Tie-2 Antibody (83715) [PE/Cy5.5] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Tie‑2
Ala23-Lys745
Accession # AAA61139
Specificity
Detects human Tie-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tie‑1, recombinant mouse Tie-2, or recombinant zebrafish Tie-2 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TEK
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Tie-2 Antibody (83715) [PE/Cy5.5]

  • angiopoietin-1 receptor
  • CD202b antigen
  • CD202b
  • EC 2.7.10
  • EC 2.7.10.1
  • hTIE2
  • p140 TEK
  • soluble TIE2 variant 1
  • soluble TIE2 variant 2
  • TEK tyrosine kinase, endothelial
  • TEK
  • Tie2
  • Tie-2
  • TIE2CD202b
  • Tunica interna endothelial cell kinase
  • Tyrosine-protein kinase receptor TEK
  • Tyrosine-protein kinase receptor TIE-2
  • venous malformations, multiple cutaneous and mucosal
  • VMCM
  • VMCM1

Background

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TEK