Rat STAT5b ELISA Kit (Colorimetric)

STAT5B is encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

We have publications tested in 1 application: ELISA.

Showing Publication 1 - 1 of 1.

Publication using NBP2-80282	Applications	Species
Elbaset MA, Mohamed BMSA, Gad SA et al. Erythropoietin mitigated thioacetamide-induced renal injury via JAK2/STAT5 and AMPK pathway Scientific reports 2023-09-11 [PMID: 37697015] (ELISA)	ELISA

Array NBP2-80282

• STAT5b Antibodies
• STAT5b ELISA Kit
• STAT5b Protein