SNAP25 Antibody

SNAP 25 (synaptosome-associated protein of 25,000 dalton) is a highly conserved protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP 25 is the target of Botulinum neurotoxin A and E which cleave off 9 and 26 amino acids, respectively, from the C-terminus. The protein is part of the exocytotic fusion complex (v-SNARE) of neurons where it assembles with syntaxin 1 and synaptobrevin/VAMP. The protein is abundantly localized on the neuronal plasmalemma and on recycling vesicles including synaptic vesicles. It is also expressed in neuroendocrine cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: WB.

Showing Publications 1 - 4 of 4.

Publications using NB100-1492	Applications	Species
Kumar S, Orlov E, Gowda P et al. Synaptosome microRNAs regulate synapse functions in Alzheimer's disease NPJ genomic medicine 2022-08-08 [PMID: 35941185] (WB, Mouse)	WB	Mouse
Mouton-Liger F, Sahun I, Collin T et al. Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: Implications for Down syndrome. Neurobiol Dis 2014-03-01 [PMID: 24291518] (WB, Rat)	WB	Rat
Guedj F, Pereira PL, Najas S et al. DYRK1A: A master regulatory protein controlling brain growth. Neurobiol Dis. 2012-01-26 [PMID: 22293606]
Voeller KK. Attention-deficit hyperactivity disorder (ADHD). J Child Neurol 2004-10-01 [PMID: 15559895]

Array NB100-1492

• SNAP25 Antibodies
• SNAP25 ELISA Kits
• SNAP25 Lysate
• SNAP25 Proteins