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SMG6 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: SMG6 Antibody [NBP1-92410] - Staining of human cell line U-251 MG shows localization to nucleoli.
Immunohistochemistry-Paraffin: SMG6 Antibody [NBP1-92410] - Staining of human cerebellum shows distinct cytoplasmic and nucleolar/ nuclear positivity in Purkinje cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SMG6 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRNKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMG6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
SMG6 Protein (NBP1-92410PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (85%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SMG6 Antibody

  • C17orf31
  • EST1 telomerase component homolog A
  • EST1A
  • EST1-like protein A
  • ever shorter telomeres 1A
  • hSmg5/7a
  • KIAA0732
  • smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
  • SMG-6
  • telomerase subunit EST1A
  • telomerase-binding protein EST1A

Background

SMG6 is involved in nonsense-mediated mRNA decay (Fukuhara et al., 2005 (PubMed 15721257)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for SMG6 Antibody (NBP1-92410) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SMG6
Entrez
Uniprot