Novus Biologicals products are now on bio-techne.com

SLC6A4/5-HTTLPR/Serotonin transporter Antibody

Images

 
Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NB100-1892] - Human Colon lysate, 35 ug protein in RIPA buffer. Antibody at 2 ug/mL. Detection by chemiluminescence.
Immunocytochemistry/ Immunofluorescence: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NB100-1892] - Analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

SLC6A4/5-HTTLPR/Serotonin transporter Antibody Summary

Immunogen
Peptide with sequence C-LHQGERETWGK corresponding to internal region according to NP_001036.1.
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SLC6A4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 10 ug/mL
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 1 - 3 ug/mL
Application Notes
Use in ICC on PC12 reported by customer review (antibody at 5ug/mL o/n at 4C). WB: Approx. 70 kDa band observed in human colon lysates (calculated MW of 70.3 kDa band according to NP_001036.1).
Control
Human Duodenum Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publication using NB100-1892.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SLC6A4/5-HTTLPR/Serotonin transporter Antibody

  • 5HT transporter
  • 5-HT Transporter
  • 5-HTT
  • 5HTTLPR
  • 5-HTTLPR
  • hSERT
  • HTT5-hydroxytryptamine transporter
  • Na+/Cl- dependent serotonin transporter
  • OCD1
  • Serotonin Transporter 1
  • SERT
  • SLC6A4
  • sodium-dependent serotonin transporter
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4,5-HTTLPR
  • Solute carrier family 6 member 4,5HTT

Background

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-22164
Species: Hu(-), Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
NBP3-12251
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
DBD00
Species: Hu
Applications: ELISA
NB100-1780
Species: Hu, Mu
Applications: Flow, PEP-ELISA, WB
NBP2-38868
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NLS3921
Species: Hu, Pm, Pm
Applications: IHC, IHC-P
NBP2-21590
Species: Hu, Mu
Applications: ICC/IF, IHC-Fr, Simple Western, WB
NBP1-86922
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-26091
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
NBP1-47977
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
NBP1-31528
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NBP3-25443
Species: Hu, Mu, Rt
Applications: Func, ICC/IF, IHC, IHC-P, WB
NB100-74555
Species: Hu, Mu, Pm, Rb, Rt
Applications: Flow, ICC/IF, IHC-FrFl, IHC, IHC-Fr, IHC-P, IP, WB
H00006999-B01P
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NB100-56350
Species: Hu, Mu, Rt
Applications: WB
NB300-109
Species: Ch, Dr, Hu, I, Ma, Mu, Rt
Applications: Dual ISH-IHC, ICC/IF, IHC-FrFl, IHC-WhMt, IHC, IHC-Fr, IHC-P, KO, Simple Western, WB
MAB5764
Species: Hu
Applications: CyTOF-ready, Flow, IHC
NB100-1892
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF

Publications for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (NB100-1892)(1)


Showing Publication 1 - 1 of 1.
Publication using NB100-1892 Applications Species
Voeller KK. Attention-deficit hyperactivity disorder (ADHD). J Child Neurol 2004-10-01 [PMID: 15559895]

Reviews for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (NB100-1892) (0)

There are no reviews for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (NB100-1892). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (NB100-1892) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional SLC6A4/5-HTTLPR/Serotonin transporter Products

Research Areas for SLC6A4/5-HTTLPR/Serotonin transporter Antibody (NB100-1892)

Find related products by research area.

Blogs on SLC6A4/5-HTTLPR/Serotonin transporter.

Epigenetics of Depression: How Can Psychological Stress Alter Your DNA?
By Emily Cartwright, PhDHow Can Psychological Stress Alter Your DNA? Traumatic events, work demands, relationship conflicts, and health problems are all examples of psychological stressors that can result in phy...  Read full blog post.

Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SLC6A4/5-HTTLPR/Serotonin transporter Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol SLC6A4
Entrez
Uniprot