Home » SF-1/NR5A1/Steroidogenic Factor 1 » SF-1/NR5A1/Steroidogenic Factor 1 Antibodies » SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/4368R) [CoraFluor™ 1]
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SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/4368R) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IHC
Clone
NR5A1/4368R
Clonality
Monoclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-14291AF350
Alexa Fluor 405
NBP3-14291AF405
Alexa Fluor 488
NBP3-14291AF488
Alexa Fluor 532
NBP3-14291AF532
Alexa Fluor 594
NBP3-14291AF594
Alexa Fluor 647
NBP3-14291AF647
Alexa Fluor 700
NBP3-14291AF700
Alexa Fluor 750
NBP3-14291AF750
Allophycocyanin
NBP3-14291APC
Biotin
NBP3-14291B
DyLight 350
NBP3-14291UV
DyLight 405
NBP3-14291V
DyLight 488
NBP3-14291G
DyLight 550
NBP3-14291R
DyLight 594
NBP3-14291DL594
DyLight 650
NBP3-14291C
DyLight 680
NBP3-14291FR
DyLight 755
NBP3-14291IR
FITC
NBP3-14291F
HRP
NBP3-14291H
Janelia Fluor 525
NBP3-14291JF525
Janelia Fluor 549
NBP3-14291JF549
Janelia Fluor 646
NBP3-14291JF646
Janelia Fluor 669
NBP3-14291JF669
PE
NBP3-14291PE
PerCP
NBP3-14291PCP
Unconjugated
NBP3-13917-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-13917-100ug
Azide and BSA Free
NBP3-14291
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SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/4368R) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment of human SF-1/NR5A1/Steroidogenic Factor 1 protein (exact sequence is proprietary) (Uniprot: Q13285)
Localization
Nuclear
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
NR5A1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/4368R) [CoraFluor™ 1]

  • AD4BP
  • AD4BPSTF-1
  • Adrenal 4-binding protein
  • ELP
  • FTZ1adrenal 4 binding protein
  • FTZF1
  • FTZF1nuclear receptor AdBP4
  • Fushi tarazu factor homolog 1
  • NR5A1
  • Nuclear receptor subfamily 5 group A member 1
  • nuclear receptor subfamily 5, group A, member 1
  • SF1
  • SF-1
  • SF-1POF7
  • SF1steroidogenic factor 1
  • Steroid hormone receptor Ad4BP
  • steroidogenic factor-1

Background

Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NR5A1