SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/3397) [Janelia Fluor® 669] Summary
Immunogen |
Recombinant fragment (around aa220-461) of human SF-1/NR5A1/Steroidogenic Factor 1 protein (Uniprot: Q13285) |
Localization |
Nuclear |
Isotype |
IgG2b Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
NR5A1 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Paraffin
- Protein Array
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NR5A1/3397) [Janelia Fluor® 669]
Background
Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NBP3-08624JF669) (0)
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FAQs for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (NBP3-08624JF669) (0)
Secondary Antibodies
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Isotype Controls
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