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Recombinant Human Relaxin R2/LGR8 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications AP

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Recombinant Human Relaxin R2/LGR8 Protein Summary

Description
An untagged recombinant protein corresponding to the amino acid sequence of (AAI48730.1) for Human Relaxin R2/LGR8

Source: Wheat Germ (in vitro) with proprietary liposome technology

Amino Acid Sequence: MIVFLVFKHLFSLRLITMFFLLHFIVLINVKDFALTQGSMITPSCQKGYFPCGNLTKCLPRAFHCDGKDDCGNGADEENCGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWMESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWNKDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTALQTTEVRNCFGREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWIVIFFLPVNSALNPILYTLTTNFFKDKLKQLLHKHQRKSIFKIKKKSLSTSIVWIEDSSSLKLGVLNKITLGDSIMKPVS

Preparation
Method
in vitro wheat germ expression system with proprietary liposome technology
Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Recombinant Protein
Gene
RXFP2
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Immunoaffinity Purification
Theoretical MW
82.94 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
25 mM Tris-HCl pH8.0 in 2% glycerol.
Preservative
Glycerol
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human Relaxin R2/LGR8 Protein

  • G protein coupled receptor affecting testicular descent
  • Gpr106
  • GPR106G-protein coupled receptor 106
  • Great
  • GREATRelaxin family peptide receptor 2
  • INSL3R
  • leucine-rich repeat-containing G protein-coupled receptor 8
  • Leucine-rich repeat-containing G-protein coupled receptor 8
  • Lgr8
  • LGR8.1
  • LGR8G-protein coupled receptor affecting testicular descent
  • Relaxin R2
  • relaxin receptor 2
  • relaxin/insulin-like family peptide receptor 2
  • RelaxinR2
  • RLN2R
  • Rxfp2
  • RXFPR2

Background

LGR8 is a member of the Relaxin Receptor subfamily. LGR8 has been shown to be important for testis descent. LGR8 has been reported in blood, bone marrow, brain, kidney, muscle, testis, thyroid, and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RXFP2