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Relaxin R2/LGR8 Antibody (1013903) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with (A) human Relaxin R2 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Relaxin R2 Monoclonal Antibody (Catalog # MAB102501) followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
1013903
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Relaxin R2/LGR8 Antibody (1013903) [Unconjugated] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Relaxin R2
Met1-Asn416
Accession # Q8WXD0
Specificity
Detects human Relaxin R2 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Relaxin R2/LGR8 Antibody (1013903) [Unconjugated]

  • G protein coupled receptor affecting testicular descent
  • Gpr106
  • GPR106G-protein coupled receptor 106
  • Great
  • GREATRelaxin family peptide receptor 2
  • INSL3R
  • leucine-rich repeat-containing G protein-coupled receptor 8
  • Leucine-rich repeat-containing G-protein coupled receptor 8
  • Lgr8
  • LGR8.1
  • LGR8G-protein coupled receptor affecting testicular descent
  • Relaxin R2
  • relaxin receptor 2
  • relaxin/insulin-like family peptide receptor 2
  • RelaxinR2
  • RLN2R
  • Rxfp2
  • RXFPR2

Background

Relaxin R2 (also known as LGR8) is the G-protein coupled receptor (GPCR) for Relaxin, and may also be a receptor for INSL3. LGR8 can mediate the action of Relaxin through cAMP-dependent pathway distinct from structurally related insulin and insulin-like growth factor family ligand. Distribution of this receptor implicates its role in reproductive, brain, renal, cardiovascular and other functions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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