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Reduced Folate Carrier/SLC19A1 Antibody (890513) [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      FAB8450JF585
    • Availability
      Product Discontinued

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Reduced Folate Carrier/SLC19A1 Antibody (890513) [Janelia Fluor® 585] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Reduced Folate Carrier/SLC19A1
Met1-Gln591
Accession # P41440
Specificity
Stains human Reduced Folate Carrier/SLC19A1 transfectants but not irrelevant transfectants in flow cytometry.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SLC19A1
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Reduced Folate Carrier/SLC19A1 Antibody (890513) [Janelia Fluor® 585]

  • CHMD
  • FLOT1
  • folate transporter 1
  • FOLT
  • FOLThuman reduced folate carrier (RFC)10Intestinal folate carrier 1
  • IFC1
  • IFC-1
  • Placental folate transporter
  • Reduced folate carrier protein
  • REFC
  • RFC
  • RFC1
  • SLC19A1
  • solute carrier family 19 (folate transporter), member 1
  • Solute carrier family 19 member 1

Background

Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC19A1