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Reduced Folate Carrier/SLC19A1 Antibody (890513) [Allophycocyanin]

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HEK293 human embryonic kidney cell line transfected with human SLC19A1 and eGFP were stained with either (A) Mouse Anti-Human Reduced Folate Carrier/SLC19A1 APC-conjugated Monoclonal Antibody (Catalog # FAB8450A) or (B) ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
890513
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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Reduced Folate Carrier/SLC19A1 Antibody (890513) [Allophycocyanin] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Reduced Folate Carrier/SLC19A1
Met1-Gln591
Accession # P41440
Specificity
Stains human Reduced Folate Carrier/SLC19A1 transfectants but not irrelevant transfectants in flow cytometry.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SLC19A1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Reduced Folate Carrier/SLC19A1 Antibody (890513) [Allophycocyanin]

  • CHMD
  • FLOT1
  • folate transporter 1
  • FOLT
  • FOLThuman reduced folate carrier (RFC)10Intestinal folate carrier 1
  • IFC1
  • IFC-1
  • Placental folate transporter
  • Reduced folate carrier protein
  • REFC
  • RFC
  • RFC1
  • SLC19A1
  • solute carrier family 19 (folate transporter), member 1
  • Solute carrier family 19 member 1

Background

SLC19A1, also known as Reduced Folate Carrier protein, is a multi-pass transmembrane transporter that is involved in the regulation of intracellular concentrations of folate. There is an association between idiopathic Recurrent Spontaneous Abortion (RSA) and SLC19A1 polymorphisms that may be useful biomarkers for RSA risk. Three transcript variants encoding different isoforms have been found for this gene. Human and mouse SLC19A1 share only 58% amino acid (aa) sequence identity, with considerable divergence over the C-terminal 100 aa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC19A1
Uniprot