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Rad21 Antibody [FITC]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-203AF350
Alexa Fluor 405
NB100-203AF405
Alexa Fluor 488
NB100-203AF488
Alexa Fluor 532
NB100-203AF532
Alexa Fluor 594
NB100-203AF594
Alexa Fluor 647
NB100-203AF647
Alexa Fluor 700
NB100-203AF700
Alexa Fluor 750
NB100-203AF750
Allophycocyanin
NB100-203APC
Biotin
NB100-203B
CoraFluor 1
NB100-203CL1
DyLight 350
NB100-203UV
DyLight 405
NB100-203V
DyLight 488
NB100-203G
DyLight 550
NB100-203R
DyLight 594
NB100-203DL594
DyLight 650
NB100-203C
DyLight 680
NB100-203FR
DyLight 755
NB100-203IR
HRP
NB100-203H
Janelia Fluor 525
NB100-203JF525
Janelia Fluor 549
NB100-203JF549
Janelia Fluor 585
NB100-203JF585
Janelia Fluor 635
NB100-203JF635
Janelia Fluor 646
NB100-203JF646
Janelia Fluor 669
NB100-203JF669
PE
NB100-203PE
PerCP
NB100-203PCP
Unconjugated
NB100-203
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Rad21 Antibody [FITC] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 575 and the C-terminus (residue 631) human Rad21 homolog using the numbering given in entry NP_006256.1 (GeneID 5885).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RAD21
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Rad21 Antibody [FITC]

  • double-strand-break repair protein rad21 homolog
  • hHR21FLJ25655
  • HR21
  • KIAA0078RAD21 (S. pombe) homolog
  • MCD1
  • Nuclear matrix protein 1
  • NXP-1
  • NXP1HRAD21
  • protein involved in DNA double-strand break repair
  • RAD21 homolog (S. pombe)
  • SCC1 homolog
  • SCC1FLJ40596

Background

The cohesin complex plays an important role in tethering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys the cohesin complex by means of cleavaging its Scc1 subunit (Mcd1/Scc1/hRad21), allowing the chromatids to separate and divide with the cell. During apoptosis the C-terminal portion of hRad21 is cleaved and translocated to the cytoplasm. This cleavage and translocation may act as a nuclear signal that promotes and accelerates subsequent events of apoptosis (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Testisin/Prss21
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Immunohistochemistry Testisin/Prss21 Antibody
Western Blot Testisin/Prss21 Antibody
Species: Mu, Rt
Applications: IHC, WB
SA1 Antibody
NBP1-87097
Western Blot SA1 Antibody
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NBP2-52911
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Rad21 Antibody
[FITC]
NB100-203F
Rad21 Antibody [FITC]
Species: Hu, Mu
Applications: WB, IP

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RAD21