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Properdin Antibody (062-260 (10-24))

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-64677
    • Availability
      Product Discontinued

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Properdin Antibody (062-260 (10-24)) Summary

Immunogen
Purified Human factor P from human serum
Specificity
NB100-64677 recognizes human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. NB100-64677 does not inhibit function of complement factor P.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CFP
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Western Blot
Control
Properdin Overexpression Lysate

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Borate buffered saline
Preservative
<0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Properdin Antibody (062-260 (10-24))

  • BFD
  • CFP
  • Complement Factor P
  • complement factor properdin
  • PFC
  • PFCcomplement
  • PFD
  • Properdin

Background

PFC( AAH15756, 1 a.a. - 470 a.a.) full-length recombinant protein with GST.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CFP
Entrez
Uniprot