Immunogen | Purified Human factor P from human serum |
Specificity | NB100-64677 recognizes human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. NB100-64677 does not inhibit function of complement factor P. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CFP |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Control |
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Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer | Borate buffered saline |
Preservative | <0.1% Sodium Azide |
Concentration | 1.0 mg/ml |
Purity | Protein A purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Properdin Antibody (NB100-64677)Find related products by research area.
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