PML Protein Antibody Summary
Immunogen |
The immunogen recognized by this antibody maps to a region between residue 575 and 625 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
PML |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:200- 1:1000
- Immunohistochemistry-Paraffin 1:200-1:1000
- Immunoprecipitation 2-5 ug/mg lysate
- Western Blot 1:2000-1:10000
|
Application Notes |
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections. |
Publications |
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Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
TBS and 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for PML Protein Antibody
Background
PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PML Protein Antibody (NB100-59788)(2)
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