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PKM2 Antibody (1B10) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
1B10
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-42686AF350
Alexa Fluor 405
NBP2-42686AF405
Alexa Fluor 488
NBP2-42686AF488
Alexa Fluor 532
NBP2-42686AF532
Alexa Fluor 594
NBP2-42686AF594
Alexa Fluor 647
NBP2-42686AF647
Alexa Fluor 700
NBP2-42686AF700
Alexa Fluor 750
NBP2-42686AF750
Biotin
NBP2-42686B
DyLight 350
NBP2-42686UV
DyLight 405
NBP2-42686V
DyLight 488
NBP2-42686G
DyLight 550
NBP2-42686R
DyLight 650
NBP2-42686C
DyLight 680
NBP2-42686FR
DyLight 755
NBP2-42686IR
FITC
NBP2-42686F
HRP
NBP2-42686H
Janelia Fluor 549
NBP2-42686JF549
Janelia Fluor 646
NBP2-42686JF646
Unconjugated
NBP2-42686
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-42686
BSA Free
NBP2-42686
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PKM2 Antibody (1B10) [DyLight 594] Summary

Immunogen
Recombinant human PKM2 (1-531aa) purified from E.coli.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PKM
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PKM2 Antibody (1B10) [DyLight 594]

  • CTHBP
  • Cytosolic thyroid hormone-binding protein
  • MGC3932
  • OIP3
  • OIP-3
  • OIP3EC 2.7.1.40
  • Opa-interacting protein 3
  • p58
  • PK, muscle type
  • PK2
  • PK3
  • PK3PKM
  • PKM2
  • Pyruvate kinase 2/3
  • pyruvate kinase isozymes M1/M2
  • Pyruvate kinase muscle isozyme
  • pyruvate kinase, muscle
  • TCB
  • THBP1
  • THBP1p58
  • Thyroid hormone-binding protein 1
  • thyroid hormone-binding protein, cytosolic
  • Tumor M2-PK

Background

PKM2 is encoded by this gene is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PKM