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PIDD Antibody (Lise-1) - BSA Free

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Western Blot: MDA5 Antibody (Hely-1) [NBP3-11673] - Mouse PIDD is detected in primary MEF cells using MDA5 antibody (Hely-1). Method:Cell extracts from mouse embryo fibroblasts (MEFs) either from WT (A-B) or PIDD KO ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
Lise-1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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PIDD Antibody (Lise-1) - BSA Free Summary

Immunogen
Mouse PIDD (Death Domain).
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PIDD1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 10% glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for PIDD Antibody (Lise-1) - BSA Free

  • leucine-rich repeat and death domain-containing protein
  • leucine-rich repeats and death domain containing
  • MGC16925
  • p53-induced protein with a death domain
  • PIDD

Background

The protein encoded by the LRDD gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PIDD1