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Peroxiredoxin 6 Antibody (22E7) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF
Clone
22E7
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-59436AF350
Alexa Fluor 405
NBP2-59436AF405
Alexa Fluor 488
NBP2-59436AF488
Alexa Fluor 532
NBP2-59436AF532
Alexa Fluor 594
NBP2-59436AF594
Alexa Fluor 647
NBP2-59436AF647
Alexa Fluor 700
NBP2-59436AF700
Alexa Fluor 750
NBP2-59436AF750
Biotin
NBP2-59436B
CoraFluor 1
NBP2-59436CL1
DyLight 350
NBP2-59436UV
DyLight 405
NBP2-59436V
DyLight 488
NBP2-59436G
DyLight 550
NBP2-59436R
DyLight 594
NBP2-59436DL594
DyLight 650
NBP2-59436C
DyLight 680
NBP2-59436FR
DyLight 755
NBP2-59436IR
FITC
NBP2-59436F
HRP
NBP2-59436H
Janelia Fluor 525
NBP2-59436JF525
Janelia Fluor 549
NBP2-59436JF549
Janelia Fluor 585
NBP2-59436JF585
Janelia Fluor 635
NBP2-59436JF635
Janelia Fluor 646
NBP2-59436JF646
Janelia Fluor 669
NBP2-59436JF669
PE
NBP2-59436PE
PerCP
NBP2-59436PCP
Unconjugated
NBP2-59436-100ul
mFluor Violet 450 SE
NBP2-59436MFV450
mFluor Violet 500 SE
NBP2-59436MFV500
mFluor Violet 610 SE
NBP2-59436MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-59436-100ul
BSA Free
NBP2-59436-100ul
BSA Free
NBP2-59436-50ul
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Peroxiredoxin 6 Antibody (22E7) [Allophycocyanin] Summary

Immunogen
Recombinant human Peroxiredoxin 6 (1-224aa) purified from E. coli
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PRDX6
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Peroxiredoxin 6 Antibody (22E7) [Allophycocyanin]

  • 1-Cys
  • 24 kDa protein
  • Acidic calcium-independent phospholipase A2
  • aiPLA2
  • aiPLA21-Cys PRX
  • Antioxidant protein 2
  • AOP2
  • AOP2Non-selenium glutathione peroxidase
  • EC 1.11.1.15
  • EC 1.11.1.7
  • EC 3.1.1.-
  • KIAA0106Red blood cells page spot 12
  • Liver 2D page spot 40
  • MGC46173
  • NSGPx
  • NSGPx1-Cys peroxiredoxin
  • p29
  • Peroxiredoxin 6
  • peroxiredoxin-6
  • PRDX6
  • PRX

Background

FUNCTION: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Note=Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin . MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Peroxiredoxin 6 Antibody (22E7) [Allophycocyanin]
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Bioinformatics

Gene Symbol PRDX6