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PAR1/Thrombin Receptor Antibody (731115) [Phycoerythrin]

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Human peripheral blood platelets were stained with Mouse Anti-Human Integrin a2b/CD41 APC-conjugated Monoclonal Antibody (Catalog # FAB7616A) and either (A) Mouse Anti-Human PAR1 PE-conjugated Monoclonal Antibody (Catalog # FAB3855P) or (B) Mouse IgG2BPhycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood platelets were stained with Mouse Anti-Human Integrin a2b/CD41 APC-conjugated Monoclonal Antibody (Catalog # FAB7616A) and either (A) Mouse Anti-Human PAR1 PE-conjugated Monoclonal Antibody ...read more
HT‑29 human colon adenocarcinoma cell line was stained with Mouse Anti-Human PAR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB3855P, filled histogram) or isotype control antibody (Catalog # IC0041P, ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
731115
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3855U-100UG
Alexa Fluor 405
FAB3855V-100UG
Alexa Fluor 488
FAB3855G
Alexa Fluor 532
FAB3855X
Alexa Fluor 594
FAB3855T-100UG
Alexa Fluor 647
FAB3855R-100UG
Alexa Fluor 700
FAB3855N-100UG
Alexa Fluor 750
FAB3855S-100UG
Allophycocyanin
FAB3855A
Allophycocyanin/Cy7
FAB3855APCCY7
Biotin
FAB3855B
CoraFluor 1
FAB3855CL1
DyLight 350
FAB3855D
DyLight 405
FAB3855E
DyLight 488
FAB3855K
DyLight 550
FAB3855L
DyLight 594
FAB3855M
DyLight 650
FAB3855W
DyLight 680
FAB3855Y
DyLight 755
FAB3855Z
FITC
FAB3855F
HRP
FAB3855H
Janelia Fluor 525
FAB3855JF525
Janelia Fluor 549
FAB3855I
Janelia Fluor 646
FAB3855J
Janelia Fluor 669
FAB3855JF669
PE/Atto594
FAB3855PEATT594
PE/Cy5.5
FAB3855PECY55
PE/Cy7
FAB3855PECY7
PerCP
FAB3855C
Unconjugated
MAB3855
mFluor Violet 450 SE
FAB3855MFV450
mFluor Violet 500 SE
FAB3855MFV500
mFluor Violet 610 SE
FAB3855MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3855
Carrier Free
MAB3855
Carrier Free
FAB3855A
Carrier Free
FAB3855G
Carrier Free
MAB3855-SP
Carrier Free
FAB3855V-100UG
Carrier Free
FAB3855U-100UG
Carrier Free
FAB3855T-100UG
Carrier Free
FAB3855S-100UG
Carrier Free
FAB3855R-100UG
Carrier Free
FAB3855N-100UG
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PAR1/Thrombin Receptor Antibody (731115) [Phycoerythrin] Summary

Immunogen
E. coli-derived recombinant human PAR1
Arg27-Thr102, Ser375-Thr425
Accession # P25116
Specificity
Detects human PAR1 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
F2R
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publication using
FAB3855P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PAR1/Thrombin Receptor Antibody (731115) [Phycoerythrin]

  • Cf2r
  • CF2RHTR
  • coagulation factor II (thrombin) receptor
  • Coagulation factor II receptor
  • F2R
  • HTR
  • PAR1
  • PAR1PAR-1protease-activated receptor 1
  • Protease-Activated Receptor 1
  • Thrombin receptor
  • ThrR
  • TRGPC
  • TRproteinase-activated receptor 1

Background

Human Proteinase-Activated Receptor 1 (hPAR1), also known as thrombin receptor, is a 65-70 kDa, 399 amino acid long member of the seven-transmembrane superfamily of cell-surface G protein-coupled receptors. PAR1 is activated by thrombin cleavage of its N-terminal propeptide in the extracellular domain. Human PAR1 is widely expressed in many cell types including endothelial cells, and it has been implicated in a variety of inflammatory responses. Over the regions used as immunogen, human and mouse PAR1 proteins are 58% identical in the region spanning the propeptide and extracellular domains, and 84% identical in the cytoplasmic tail.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PAR1/Thrombin Receptor Antibody (FAB3855P)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Bioinformatics

Gene Symbol F2R
Uniprot