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p57 Kip2 Antibody (KIP2/8169R) [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
KIP2/8169R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 650

Order Details

p57 Kip2 Antibody (KIP2/8169R) [DyLight 650] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant full-length human p57 Kip2 protein
Localization
Nucleus.
Specificity
Recognizes a protein of 57kDa, identified as p57 Kip2 It shows no cross-reaction with p27Kip1
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CDKN1C
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for p57 Kip2 Antibody (KIP2/8169R) [DyLight 650]

  • Beckwith-Wiedemann syndrome
  • BWS
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • cyclin-dependent kinase inhibitor 1C
  • Cyclin-dependent kinase inhibitor p57
  • KIP2BWCR
  • p57
  • p57Kip2
  • WBS

Background

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CDKN1C