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p57 Kip2 Antibody (KIP2/8169R) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
KIP2/8169R
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 532

Order Details

p57 Kip2 Antibody (KIP2/8169R) [Alexa Fluor® 532] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant full-length human p57 Kip2 protein
Localization
Nucleus.
Specificity
Recognizes a protein of 57kDa, identified as p57 Kip2 It shows no cross-reaction with p27Kip1
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CDKN1C
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for p57 Kip2 Antibody (KIP2/8169R) [Alexa Fluor® 532]

  • Beckwith-Wiedemann syndrome
  • BWS
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • cyclin-dependent kinase inhibitor 1C
  • Cyclin-dependent kinase inhibitor p57
  • KIP2BWCR
  • p57
  • p57Kip2
  • WBS

Background

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional p57 Kip2 Products

Array NBP3-20897AF532

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Bioinformatics

Gene Symbol CDKN1C