p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646] Summary
Immunogen |
Recombinant full-length human p57 Kip2 protein |
Localization |
Nucleus. |
Specificity |
Recognizes a protein of 57kDa, identified as p57 Kip2 It shows no cross-reaction with p27Kip1 |
Isotype |
IgG Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
CDKN1C |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Paraffin
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]
Background
p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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