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p57 Kip2 Antibody (KIP2/7187) [DyLight 488]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clone
KIP2/7187
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-20895AF350
Alexa Fluor 405
NBP3-20895AF405
Alexa Fluor 488
NBP3-20895AF488
Alexa Fluor 532
NBP3-20895AF532
Alexa Fluor 594
NBP3-20895AF594
Alexa Fluor 647
NBP3-20895AF647
Alexa Fluor 700
NBP3-20895AF700
Alexa Fluor 750
NBP3-20895AF750
Allophycocyanin
NBP3-20895APC
Biotin
NBP3-20895B
CoraFluor 1
NBP3-20895CL1
DyLight 350
NBP3-20895UV
DyLight 405
NBP3-20895V
DyLight 550
NBP3-20895R
DyLight 594
NBP3-20895DL594
DyLight 650
NBP3-20895C
DyLight 680
NBP3-20895FR
DyLight 755
NBP3-20895IR
FITC
NBP3-20895F
HRP
NBP3-20895H
Janelia Fluor 525
NBP3-20895JF525
Janelia Fluor 549
NBP3-20895JF549
Janelia Fluor 585
NBP3-20895JF585
Janelia Fluor 635
NBP3-20895JF635
Janelia Fluor 646
NBP3-20895JF646
Janelia Fluor 669
NBP3-20895JF669
PE
NBP3-20895PE
PerCP
NBP3-20895PCP
Unconjugated
NBP3-20437-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-20437-100ug
Azide and BSA Free
NBP3-20895
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p57 Kip2 Antibody (KIP2/7187) [DyLight 488] Summary

Immunogen
Recombinant full-length human p57 Kip2 protein
Localization
Nucleus.
Specificity
Recognizes a protein of 57kDa, identified as p57 Kip2 It shows no cross-reaction with p27Kip1
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CDKN1C
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for p57 Kip2 Antibody (KIP2/7187) [DyLight 488]

  • Beckwith-Wiedemann syndrome
  • BWS
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • cyclin-dependent kinase inhibitor 1C
  • Cyclin-dependent kinase inhibitor p57
  • KIP2BWCR
  • p57
  • p57Kip2
  • WBS

Background

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDKN1C